1 Result for "

BIO8169

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BIO8169" in MCE Product Catalog:

Cat. No.: HY-158374
CAS No.: 2792153-06-9
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

BIO-8169 is a selective inhibitor for interleukin receptor-associated kinase 4 (IRAK 4), with an IC50 of 0.23 nM. BIO-8169 exhibits good pharmacokinetic character, reduces the production of pro-inflammatory cytokines, and attenuates the autoimmune encephalomyelitis in EAE mice model. BIO-8169 exhibits good blood brain penetrant with a rat Kpu,u of 0.7 .
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