7 Results for "

BRCC36

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "BRCC36" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N6712
CAS No.: 87-11-6
Synonyms: Acetopyrrothin
Thiolutin (Acetopyrrothin) is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. Thiolutin can be produced by Streptomyces. Thiolutin inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM). Thiolutin is a dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects. Thiolutin effectively suppresses the interaction between BRCC36 and HMGCR, leading to the inhibition of HCC growth. Thiolutin attenuates pyroptosis and NLRP3 inflammasome activation. Thiolutin markedly alleviates renal injury and inflammatory process in IgAN. Thiolutin is an anti-angiogenic compound which can ease Doxorubicin-induced cardiotoxicity (DOXIC) [1][2][3][4][5].
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Cat. No.: HY-168219
CAS No.: 3042887-70-4
Target:  

Deubiquitinase

Research Areas:  

Inflammation/Immunology

JMS-175-2 is a potent agonist of BRCC36 isopeptidase complex (BRISC), with the IC50 of 3.8 μM. JMS-175-2 plays an important role in Type I interferon-mediated diseases .
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Cat. No.: HY-N6712R
CAS No.: 87-11-6
Synonyms: Acetopyrrothin (Standard)
Thromycin (Standard) is the analytical standard of thromycin (Acetopyrrothin) (HY-N6712). Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. Thiolutin can be produced by Streptomyces. Thiolutin inhibits AMSH (IC50 = 4 μM) and Rpn11 (IC50 = 0.53 μM). Thiolutin is a dual inhibitor of BRCC36 and the NLRP3 inflammasome, exhibiting anti-inflammatory effects. Thiolutin effectively suppresses the interaction between BRCC36 and HMGCR, leading to the inhibition of HCC growth. Thiolutin attenuates pyroptosis and NLRP3 inflammasome activation. Thiolutin markedly alleviates renal injury and inflammatory process in IgAN. Thiolutin is an anti-angiogenic compound which can ease Doxorubicin (HY-15142A)-induced cardiotoxicity (DOXIC) [1][2][3][4][5].
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Cat. No.: HY-P82553
Synonyms: C6.1A; BRCC36; CXorf53

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82553A
Synonyms: C6.1A; BRCC36; CXorf53

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P72107
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRCC3; Lys-63-Specific Deubiquitinase BRCC36; Prev. CXorf53; BRCA1-A Complex Subunit BRCC36; BRCC36; BRISC Complex Subunit BRCC36; C6.1A; BRCA1/BRCA2-Containing Complex, Subunit 3; BRCA1/BRCA2-Containing Complex Subunit 36; Chromosome X Open Reading Frame
Species:  
Source:  
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Cat. No.: HY-RS01595
Research Areas:  

Others

BRCC3 Human Pre-designed siRNA Set A contains three designed siRNAs for BRCC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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