9 Results for "

Bosutinib

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Bosutinib" in MCE Product Catalog:

24
24 Cited Publications
Cat. No.: HY-10158
CAS No.: 380843-75-4
Purity:  99.89%
Synonyms: SKI-606
Target:  

Src Bcr-Abl Autophagy

Research Areas:  

Cancer

Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC50 of 1.2 nM and 1 nM, respectively .
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24
24 Cited Publications
Cat. No.: HY-10158A
CAS No.: 918639-08-4
Purity:  99.97%
Synonyms: SKI-606 hydrate
Target:  

Src Bcr-Abl

Research Areas:  

Cancer

Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50 of 1.2 nM and 1 nM, respectively .
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Cat. No.: HY-103029
CAS No.: 1391063-17-4
Purity:  99.62%
Target:  

Wee1

Research Areas:  

Cancer

Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively .
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Cat. No.: HY-10158S
Synonyms: SKI-606-d8
Bosutinib-d8 is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively .
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Cat. No.: HY-172091
Target:  

EGFR

Research Areas:  

Cancer

CZY43 is a HER3 degrader. CZY43 can effectively induce HER3 degradation in a dose- and time-dependent manner in breast cancer SKBR3 cells. CZY43 potently inhibits HER3-dependent signaling and cancer cell growth and outperforms Bosutinib (HY-10158) .
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Cat. No.: HY-10158AR
CAS No.: 918639-08-4
Synonyms: SKI-606 hydrate (Standard)
Research Areas:  

Cancer

Bosutinib (Standard) (SKI-606 (Standard)) hydrate is the analytical standard of Bosutinib hydrate (HY-10158A). This product is intended for research and analytical applications. Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50s of 1.2 nM and 1 nM, respectively.
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Cat. No.: HY-10158S1
Synonyms: SKI-606-13C,d3
Bosutinib- 13C,d3 (SKI-606- 13C,d3) is 13C labeled Bosutinib. Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC50 of 1.2 nM and 1 nM, respectively .
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Cat. No.: HY-171167
CAS No.: 2468737-92-8
Target:  

Drug Derivative

Research Areas:  

Cancer

Bosutinib analog-1 (compound 74) is an orally active Bosutinib (HY-10158) analog. Bosutinib analog-1 can be used for leukemia research .
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Cat. No.: HY-W770773
CAS No.: 2468737-96-2
Target:  

Drug Derivative

Research Areas:  

Cancer

Bosutinib N-Oxide (Compound 80) is a quinoline-type heterocyclic compound. Bosutinib N-Oxide shows anti-proliferative activity and can be used for research of leukemia .
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