918639-08-4
918639-08-4
Chemical Structure
Bosutinib hydrate
Synonym(s): SKI-606 hydrate
- CAS No.: 918639-08-4
- Formula:C26H31Cl2N5O4
- Molecular Weight:548.46
IUPAC Name: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile hydrate
InChIKey: BXPOSPOKHGNMEP-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(NC4=CC(OC)=C(C=C4Cl)Cl)=C(C=NC3=C2)C#N)OC.O
Biological Activity: Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50 of 1.2 nM and 1 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Bosutinib hydrate | 99.97% | Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50 of 1.2 nM and 1 nM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Bosutinib hydrate (Standard) | ≥98% | Bosutinib (Standard) (SKI-606 (Standard)) hydrate is the analytical standard of Bosutinib hydrate (HY-10158A). This product is intended for research and analytical applications. Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50s of 1.2 nM and 1 nM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.99
HY-10158Bosutinib -
Similarity Score 0.90
HY-171167Bosutinib analog-1 -
Similarity Score 0.88
HY-W770773Bosutinib N-Oxide -
Similarity Score 0.85
HY-175681CaMKIIα ligand-1 -
Similarity Score 0.85
HY-103029Bosutinib isomer -
Similarity Score 0.77
HY-10188SKS-927 -
Similarity Score 0.58
HY-116184PF-05387252 -
Similarity Score 0.56
HY-168305EGFR ligand-11 -
Similarity Score 0.55
HY-W561311M387783 -
Explore the MedChemAI to find more analogs
