4 Results for "

CEM/ADR5000 cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "CEM/ADR5000 cells" in MCE Product Catalog:

1
Isoscopoletin
Isoscopoletin
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1 Cited Publications
Cat. No.: HY-N1365
CAS No.: 776-86-3
Synonyms: 6-Hydroxy-7-methoxycoumarin
Category:  

Coumarins Plants Compositae Infection other families Monophenols Phenols Phenylpropanoids Disease Research Fields Sindora sumatrana Miq. Cancer

Target:  

HBV p38 MAPK NF-κB STAT Akt ERK JNK

Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively . Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication . Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-κB/STAT/AKT signaling pathway .
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Isoscopoletin (Standard)
Isoscopoletin (Standard)
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Cat. No.: HY-N1365R
CAS No.: 776-86-3
Synonyms: 6-Hydroxy-7-methoxycoumarin (Standard)
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants Compositae Sindora sumatrana Miq.

Target:  

Reference Standards HBV p38 MAPK NF-κB STAT Akt ERK JNK

Isoscopoletin (Standard) is the analytical standard of Isoscopoletin. This product is intended for research and analytical applications. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively . Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication . Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-κB/STAT/AKT signaling pathway .
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2',4'-Dihydroxy-3',6'-dimethoxychalcone
2',4'-Dihydroxy-3',6'-dimethoxychalcone
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Cat. No.: HY-N1665
CAS No.: 129724-43-2
Category:  

Flavonoids Chalcones Polygonaceae Phenols Polyphenols Adiantum venustum Don Plants Disease Research Fields Cancer

Target:  

Others

2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively .
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[Ru(phen)2(4-Me-Sal)]BF4
[Ru(phen)2(4-Me-Sal)]BF4
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Cat. No.: HY-157464
Target:  

Drug Derivative

Research Areas:  

Cancer

[Ru(phen)2(4-Me-Sal)]BF4 (compound 10), a Ru(II)-based polypyridyl complexe, displays outstanding antiproliferative activity against drug-sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells (IC50=0.52 μM and 5.56 μM, respectively) .
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