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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

CEM-SS cells

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) HIV (4)
By Research Areas:	Infection (6)

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Targets Recommended: Nuclear Factor of activated T Cells (NFAT) TREM receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W105741

12-Bromododecanoic acid	HIV	Infection
12-Bromododecanoic acid is a bromo fatty acid. 12-Bromododecanoic acid can be used in the synthesis of clickable forms of myristic acid. 12-Bromododecanoic acid inhibits HIV replication in CEM-SS T cells (EC₅₀ = 38 µM) .

HY-P5738

Palicourein	Bacterial	Infection
Palicourein is a 37 amino acid cyclic polypeptide. Palicourein inhibits the in vitro cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC₅₀ value of 0.1 μM and an IC₅₀ value of 1.5 μM .

HY-180566

HIV-IN-13	HIV	Infection
HIV-IN-13 (compound 7) is a potent HIV inhibitor with low cellular toxicity. HIV-IN-13 inhibits HIV in CEM-SS cells with an EC₅₀ of 1.38 μM. HIV-IN-13 displays antiviral activity in hPBMCs infected with different HIV strains (EC₅₀ = 2.01-10.7 μM), while showing low cellular toxicity (TC₅₀ >100 μM). HIV-IN-13 can be used for HIV-infection research .

HY-165513

Niruriside	HIV	Infection
Niruriside is a HIV REV/RRE complex inhibitor. Niruriside specifically inhibits the binding interaction between HIV REV protein and RRE RNA, with an IC₅₀ of 3.3 μM, and shows no significant activity against the unrelated R17 capsid protein/operator RNA binding system. At the tested concentrations, Niruriside fails to protect CEM-SS cells from acute HIV-1 infection. Niruriside can be used in the research of human immunodeficiency virus (HIV) infection .

HY-162074

Nipamovir	HIV	Infection
Nipamovir is an anti-HIV prodrug. Nipamovir is cleaved in vivo by glutathione and other active thiols. Nipamovir inhibits the replication of HIV-1_RF and HIV-1_92HT599 in cells, with EC₅₀ values of 3.64 μM and 3.23 μM, respectively. Nipamovir can be used in studies related to HIV infection .

HY-N13863

Glepidotin A	Others	Infection
Glepidotin A is a flavanol. Glepidotin A can be isolated from the leaves and stems of Glycyrrhiza lepidota. Glepidotin A exhibits no anti-HIV-1 activity .

Cat. No.	Product Name	Target	Research Area

HY-P5738

Palicourein	Bacterial	Infection
Palicourein is a 37 amino acid cyclic polypeptide. Palicourein inhibits the in vitro cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC₅₀ value of 0.1 μM and an IC₅₀ value of 1.5 μM .

Glepidotin A	Structural Classification Flavonols Flavonoids Leguminosae Plants Glycyrrhiza lepidota Pursh Source Classification	Others
Glepidotin A is a flavanol. Glepidotin A can be isolated from the leaves and stems of Glycyrrhiza lepidota. Glepidotin A exhibits no anti-HIV-1 activity .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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CEM-SS cells

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