3049284-11-6
3049284-11-6
Chemical Structure
HIV-IN-13
- CAS No.: 3049284-11-6
- Formula:C32H30F2N4O7S
- Molecular Weight:652.67
InChIKey: GQPAJOQWIOEVSI-UHFFFAOYSA-N
SMILES: FC(O1)(F)OC2=C1C=C(N(CCNC(C3=C(SCOC(CCC)=O)C=CC=C3)=O)C=C(C(NCC4=NC(C)=CC=C4)=O)C5=O)C5=C2
Biological Activity: HIV-IN-13 (compound 7) is a potent HIV inhibitor with low cellular toxicity. HIV-IN-13 inhibits HIV in CEM-SS cells with an EC50 of 1.38 μM. HIV-IN-13 displays antiviral activity in hPBMCs infected with different HIV strains (EC50 = 2.01-10.7 μM), while showing low cellular toxicity (TC50 >100 μM). HIV-IN-13 can be used for HIV-infection research[1].
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HIV-IN-13 | HIV-IN-13 (compound 7) is a potent HIV inhibitor with low cellular toxicity. HIV-IN-13 inhibits HIV in CEM-SS cells with an EC50 of 1.38 μM. HIV-IN-13 displays antiviral activity in hPBMCs infected with different HIV strains (EC50 = 2.01-10.7 μM), while showing low cellular toxicity (TC50 >100 μM). HIV-IN-13 can be used for HIV-infection research. | |||||||||||||||||||||
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References
Keywords
