Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
CLL-B cells
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "CLL-B cells" in MCE Product Catalog:
48
48 Publications Verification
Synonyms: Mitozantrone; NSC 301739
48
48 Publications Verification
Synonyms: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride
4
Research Areas:
PRT-060318 (PRT318) s a potent, selective and orally active tyrosine kinase Syk inhibitor with an IC50 of 3 nM. PRT-060318 suppresses chronic lymphocytic leukemia (CLL) B cell activation and migration, and induces apoptosis. PRT-060318 prevents Heparin (HY-17567)-induced thrombocytopenia and thrombosis in a transgenic mouse model. PRT-060318 dihydrochloride can be used for CLL and thrombus research .
4
Research Areas:
PRT-060318 (PRT318) dihydrochloride is a potent, selective and orally active tyrosine kinase Syk inhibitor with an IC50 of 3 nM. PRT-060318 dihydrochloride suppresses chronic lymphocytic leukemia (CLL) B cell activation and migration, and induces apoptosis. PRT-060318 dihydrochloride prevents Heparin (HY-17567)-induced thrombocytopenia and thrombosis in a transgenic mouse model. PRT-060318 dihydrochloride can be used for CLL and thrombus research .
Synonyms: NSC 680410
Adaphostin (NSC 680410), the adamantyl ester of AG957, is a potent p210 bcr/abl inhibitor (IC50=14 μM). Adaphostin induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 ranging from 17 to 216 nM). Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Adaphostin increased the level of reactive oxygen species (ROS) within CLL B cells .
Cat. No.: HY-13502B
CAS No.: 70711-41-0
Synonyms: Mitozantrone diacetate; NSC 301739 diacetate
Cat. No.: HY-103275R
CAS No.: 241127-58-2
Synonyms: NSC 680410 (Standard)
Target:
Research Areas:
Adaphostin (Standard) is the analytical standard of Adaphostin. This product is intended for research and analytical applications. Adaphostin (NSC 680410), the adamantyl ester of AG957, is a potent p210bcr/abl inhibitor (IC50=14 μM). Adaphostin induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 ranging from 17 to 216 nM). Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Adaphostin increased the level of reactive oxygen species (ROS) within CLL B cells .
Cat. No.: HY-13502AR
CAS No.: 70476-82-3
Synonyms: Mitozantrone dihydrochloride (Standard); NSC 301739 dihydrochloride (Standard)
Category:
Cat. No.: HY-13502AS
Synonyms: Mitozantrone-d8dihydrochloride; NSC 301739-d8 dihydrochloride
Cat. No.: HY-13502AS1
Synonyms: Mitozantrone-d8 hydrochloride; NSC 301739-d8 hydrochloride
Cat. No.: HY-13502R
CAS No.: 65271-80-9
Synonyms: Mitozantrone (Standard); NSC 301739 (Standard)
Category:
Cat. No.: HY-P992439
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
