13 Results for "

Citryl-Thioether-CoA

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Citryl-Thioether-CoA" in MCE Product Catalog:

Cat. No.: HY-CE01263
CAS No.: 72845-19-3
Synonyms: Citryl-Thioether-Coenzyme A
Research Areas:  

Metabolic Disease

Citryl-Thioether-CoA (Citryl-Thioether-Coenzyme A) is a coenzyme A derivative .
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Cat. No.: HY-172320
CAS No.: 2919596-13-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-986238 is an orally active macrocyclic peptide PD-L1 inhibitor. BMS-986238 can be used in the research of tumors such as solid tumors and lymphomas .
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Cat. No.: HY-P3440
CAS No.: 1886057-64-2
Research Areas:  

Cancer

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .
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Cat. No.: HY-P5963
CAS No.: 2983116-47-6
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. Lib2-1 can be used for autoimmune and inflammatory diseases research .
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Cat. No.: HY-P10714
CAS No.: 2396736-46-0
Research Areas:  

Cancer

Ub4ix is a DUB/26S proteasome inhibitor. Ub4ix can protect K48-linked Ub chains from being chopped up by deubiquitinating enzymes (DUBs) and prevent the proteasomal degradation of Ub-tagged proteins. Ub4ix can reduce the viability of Hela cells and induce apoptosis, with an IC50 value of 1.6 μM .
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Cat. No.: HY-161096
CAS No.: 3034861-58-7
Target:  

ROR

Research Areas:  

Cancer

Antitumor agent-127 (compound 1) is a parent macrocyclic peptide. Antitumor agent-127 displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines .
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Cat. No.: HY-P5984
CAS No.: 1453840-35-1
Target:  

mTOR

Research Areas:  

Others

Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .
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Cat. No.: HY-P5984A
Target:  

mTOR

Research Areas:  

Others

Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). Thioether-cyclized helix B peptide, CHBP (TFA) can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .
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Cat. No.: HY-P11868
PADI4_3 is a substrate-competitive and selective PADI4 inhibitor with an IC50 of 56 nM. PADI4_3 blocks citrullination of histone H3 and reduces the formation of neutrophil extracellular traps. PADI4_3 can be used in research related to autoimmune diseases and cancers .
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Cat. No.: HY-P11869
Research Areas:  

Inflammation/Immunology

PADI4_11 is an isoform-selective, allosteric PADI4 activator with a Kd of 457 nM. PADI4_11 enters cells via active transport, does not induce cytotoxicity or membrane damage, and serves as a tool for investigating the regulation, function and cellular reprogramming of PADI4. PADI4_11 can be used in studies related to rheumatoid arthritis and ulcerative colitis .
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Cat. No.: HY-P11870
Research Areas:  

Others

PADI4_7 is an inert binder of peptidylarginine deiminase IV (PADI4) with a Kd value of 8 nM. PADI4_7 binds to PADI4 but does not modulate its catalytic activity. PADI4_7 can be functionalized into a biotinylated probe (bio-PADI4_7), which enriches intracellular PADI4 from cell extracts for biochemical analyses, including the identification of PADI4-interacting proteins under resting or activated conditions .
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Cat. No.: HY-P11673
CAS No.: 2468152-46-5
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Zabopegdutide is a glucagon and glucagon-like peptide 1 (GLP-1) receptor agonist. Zabopegdutide can be used for the study of obesity .
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Cat. No.: HY-P11927
Target:  

GSK-3

Research Areas:  

Cancer

BiS3 is a selective hyperbivalent macrocyclic peptide GSK3β inhibitor, with a Kd of 0.28 nM and an IC50 of 4.8 nM against GSK3β. BiS3 is applicable to studies related to GSK3β signaling and colorectal cancer .
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