15 Results for "

Cotinine

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Cotinine" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
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Cat. No.: HY-B1178S
CAS No.: 110952-70-0
Synonyms: (±)-Cotinine-d3; (Rac)-NIH-10498-d3
(Rac)-Cotinine-d3 is the deuterium labeled (Rac)-Cotinine .
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Cat. No.: HY-W588194
CAS No.: 139427-57-9
Target:  

Drug Metabolite

Cotinine N-β-D-Glucuronide is a glucuronide conjugate of the tobacco metabolite Cotinine (HY-B1178). Cotinine N-β-D-Glucuronide is promising for research of tobacco carcinogen metabolism and cognitive function .
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Cat. No.: HY-B1178S1
CAS No.: 350818-68-7
Synonyms: (±)-Cotinine-d4; (Rac)-NIH-10498-d4
(Rac)-Cotinine-d4 is the deuterium labeled (Rac)-Cotinine .
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Cat. No.: HY-B1178R
CAS No.: 486-56-6
Synonyms: (-)-Cotinine (Standard); (S)-Cotinine (Standard); NIH-10498 (Standard)
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
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Cat. No.: HY-B1178A
CAS No.: 32162-64-4
Synonyms: (+)-Cotinine; (R)-Cotinine; (R)-NIH-10498
Target:  

nAChR

Research Areas:  

Neurological Disease

R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs .
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Cat. No.: HY-155456
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease

CD-6 is a flavonoid CYP2A6 inhibitor (IC50: 1.566 μM). CYP2A6 inhibits the metabolism of nicotine to cotinine, resulting in an increase in the amount of nicotine available in the blood, leading to increased smoking behavior. CD-6 mediates CYP2A6 inhibition and can be used in research on smoking cessation or smoking-related diseases .
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Cat. No.: HY-B1178S2
CAS No.: 2241872-22-8
Synonyms: (±)-Cotinine-d7; (Rac)-NIH-10498-d7
(Rac)-Cotinine-d7 is deuterium labeled Cotinine.
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Cat. No.: HY-150159S
Cotinine-d3 N-β-D-Glucuronide is the deuterium labeled Cotinine N-β-D-Glucuronide (HY-W588194). Cotinine N-β-D-Glucuronide is a glucuronide conjugate of the tobacco metabolite Cotinine (HY-B1178). Cotinine N-β-D-Glucuronide is promising for research of tobacco carcinogen metabolism and cognitive function .
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Cat. No.: HY-W588194S
(±)-Cotinine-N-β-Glucuronide-d3 is deuterated labeled (±)-Cotinine-N-β-Glucuronide.
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Cat. No.: HY-W739718
CAS No.: 1215561-37-7
(R,S)-Cotinine-d3 N-Oxide is the deuterium labeled (R,S)-Cotinine N-Oxide.
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Cat. No.: HY-W777620
CAS No.: 1215842-75-3
Synonyms: rac-Cotinine-13C,d3
1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone- 13C,d3 (rac-Cotinine- 13C,d3) is the deuterium and 13C-labeled 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone (HY-W588192).
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Cat. No.: HY-160251
CAS No.: 132929-88-5
Synonyms: (3'R,5k'S)-trans-3'-HydroxyCotinine glucuronide
Target:  

Drug Metabolite

Research Areas:  

Others

3-HC-Gluc ((3’R,5k’s)-trans-3’ -Hydroxycotinine glucuronide) The trans-structure of 3-HC, the main metabolite of nicotine .
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Cat. No.: HY-W749366
CAS No.: 2714418-11-6
trans-3'-Hydroxy Cotinine-d3 Acetate is the deuterium labeled trans-3'-Hydroxy Cotinine Acetate (HY-W739934).
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Cat. No.: HY-W765751
trans-3'-Hydroxy Cotinine-d3 N-b-D-Glucuronide is the deuterium labeled trans-3'-Hydroxy Cotinine N-b-D-Glucuronide.
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