41 Results for "

DAB

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "DAB" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-K1107

MCE DAB Peroxidase Substrate Kit (Purple-Blue Color) can be used for staining and color development detection in experiments such as immunohistochemistry of cells or tissues, in situ hybridization, Western blotting, and for visualizing endogenous HRP in cells or tissues.

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Cat. No.: HY-P10375
CAS No.: 1629665-96-8
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

BMS-986189 is a macrocyclic peptide PD-1/PD-L1 interaction with an IC50 of 1.03 nM inhibitor. BMS-986189 can be used for cancer research, such as human lung carcinoma cells L2987 .
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Cat. No.: HY-W047788
CAS No.: 10270-94-7
Research Areas:  

Others

H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
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Cat. No.: HY-P10950A
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

PD-L1 inhibitory peptide TFA is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). PD-L1 inhibitory peptide TFA binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide TFA is promising for research of cancers .
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Cat. No.: HY-W008024
CAS No.: 125238-99-5
Research Areas:  

Others

Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release. Fmoc-Dab(Boc)-OH can be used for the synthesis of peptides .
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Cat. No.: HY-W019032
CAS No.: 114360-56-4
Research Areas:  

Others

Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity .
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Cat. No.: HY-34611
CAS No.: 25691-37-6
Synonyms: N-Boc-L-2,4-diaminobutyric acid; Boc-DAB-OH
Target:  

Drug Intermediate ASCT

Research Areas:  

Neurological Disease Cancer

Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS .
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Cat. No.: HY-W966282
CAS No.: 189681-70-7
Synonyms: DAB-452
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research .
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Cat. No.: HY-P10950
CAS No.: 1931111-41-9
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

PD-L1 inhibitory peptide is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). PD-L1 inhibitory peptide binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide is promising for research of cancers .
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Cat. No.: HY-W005561
CAS No.: 3350-15-0
Research Areas:  

Others

H-Dab(Boc)-OMe hydrochloride is an N-terminally protected diaminobutyric acid containing two protecting groups: methoxy (OMe) and tert-butyloxycarbonyl (Boc). H-Dab(Boc)-OMe hydrochloride can be used to synthesize the bifunctional chelator H3Dpaa that can rapidly complex 68Ga under physiological conditions .
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Cat. No.: HY-RS03511
Research Areas:  

Others

DAB2 Human Pre-designed siRNA Set A contains three designed siRNAs for DAB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-151729
CAS No.: 1922891-74-4
Target:  

ADC Linkers

Research Areas:  

Others

N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-151779
CAS No.: 2250436-44-1
Target:  

ADC Linkers

Research Areas:  

Others

N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-129507
CAS No.: 189681-71-8
Synonyms: DAB-452 fumarate
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Aplindore fumarate (DAB-452 fumarate) is a dopamine D2 receptor partial agonist. Aplindore fumarate could be used in studies of Parkinson's disease and schizophrenia .
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Cat. No.: HY-P5006
CAS No.: 176714-12-8
Synonyms: d(CH2)5[Tyr(Me)2, DAB5]AVP
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of vasopressin V1a receptor, with a pA2 of 6.71 .
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Cat. No.: HY-P11004
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
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Cat. No.: HY-112114
CAS No.: 2437438-20-3
Target:  

Fluorescent Dye

Research Areas:  

Others

DAB2-DTPA is a conjugate of DTPA with two DAB used in the photooxidation experiments.
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Cat. No.: HY-P1424
CAS No.: 1061556-49-7
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Lei-Dab7 is a potent and selective SK2 (KCa2.2) channels blocker with a Kd of 3.8 nM. Lei-Dab7 shows low or no activity on KCa1, KCa3, Kv and Kir2.1 channels .
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Cat. No.: HY-P1424A
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Lei-Dab7 TFA is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 TFA exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 TFA increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.
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Cat. No.: HY-RS03510
Research Areas:  

Others

DAB1 Human Pre-designed siRNA Set A contains three designed siRNAs for DAB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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