10270-94-7
10270-94-7
Chemical Structure
H-Dab(Boc)-OH
- CAS No.: 10270-94-7
- Formula:C9H18N2O4
- Molecular Weight:218.25
IUPAC Name: (S)-2-amino-4-((tert-butoxycarbonyl)amino)butanoic acid
InChIKey: ICJFZQLAIOCZNG-LURJTMIESA-N
SMILES: O=C([C@H](CCNC(OC(C)(C)C)=O)N)O
Biological Activity: H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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H-Dab(Boc)-OH | 99.80% | H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities. | ||||||||||||||||||||
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References
- [1]. Rosowsky, et al. "Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain." Journal of medicinal chemistry 29.5 (1986): 655-660. [Content Brief]
Keywords
