1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Lei-Dab7

Lei-Dab7 

Cat. No.: HY-P1424
Handling Instructions

Lei-Dab7 is a potent and selective SK2 (KCa2.2) channels blocker with a Kd of 3.8 nM. Lei-Dab7 shows low or no activity on KCa1, KCa3, Kv and Kir2.1 channels.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Lei-Dab7 Chemical Structure

Lei-Dab7 Chemical Structure

CAS No. : 1061556-49-7

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other In-stock Forms of Lei-Dab7:

Other Forms of Lei-Dab7:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Lei-Dab7 is a potent and selective SK2 (KCa2.2) channels blocker with a Kd of 3.8 nM. Lei-Dab7 shows low or no activity on KCa1, KCa3, Kv and Kir2.1 channels[1][2].

In Vivo

Intracerebroventricular (9-5 ng) injections of Lei-Dab7 decreases locomotor activity, food intake and body weight in rats deprived of food. A dose of 3 ng Lei-Dab7 has no effect on these types of behavior[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3392.06

Formula

C141H236N46O39S6

CAS No.
Sequence Shortening

AFCNLR{Dab}CQLSCRSLGLLGKCIGDKCECVKH-NH2 (Disulfide bridge:Cys3-Cys21;Cys8-Cys26;Cys12-Cys28)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Lei-Dab7
Cat. No.:
HY-P1424
Quantity:
MCE Japan Authorized Agent: