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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
DDX1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "DDX1" in MCE Product Catalog:
1
1 Cited Publications
Sm4 is a selective and orally active SOX18 inhibitor. Sm4 inhibits SOX18-DNA binding (IC50 = 97.5 μM); Sm4 disrupts the SOX18-RBPJ protein-protein interaction (IC50 = 42.3 μM). Sm4 blocks SOX18 DNA binding, disrupts multiple SOX18 protein-protein interactions with RBPJ, DDX1, DDX17, ILF3, SOX7 and STAT1, modulates SOX18 chromatin binding dynamics. Sm4 exerts anti‑angiogenic and anti‑lymphangiogenic effects, reduces tumor vascular density, triggers vascular defects in zebrafish, prolongs survival in mouse metastatic cancer models. Sm4 can be used for the research of breast cancer [1] .
Cat. No.: HY-RS03629
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DDX1 Human Pre-designed siRNA Set A contains three designed siRNAs for DDX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17684
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Ddx1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ddx1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24145
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Ddx1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddx1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-185893
CAS No.: 3126213-85-9
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UNC11676A is an MDA5 ATPase inhibitor with IC50 values of 6 μM, 115 μM and 108 μM against MDA5, LGP2 and DDX1, respectively. MDA5, LGP2 and DDX1 are three human DExD/H-box RNA helicases. UNC11676A can be used in the research of Aicardi-Goutières syndrome, Singleton-Merten syndrome, systemic lupus erythematosus and Alzheimer's disease [1].
Cat. No.: HY-187308
CAS No.: 765922-18-7
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STK189682 is an ATPase inhibitor targeting MDA5, LGP2 and DDX1, with IC50 values of 7 μM, 7 μM and 5 μM, respectively. STK189682 binds to the MDA5-ATP complex in an ATP-noncompetitive manner and does not compete with RNA [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
