765922-18-7
765922-18-7
Chemical Structure
STK189682
- CAS No.: 765922-18-7
- Formula:C21H16N4O4S2
- Molecular Weight:452.51
InChIKey: HTUMPAOKALPGCT-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC2=NC(C3=C(C)N=C(NC(C4=CC=CC=C4)=O)S3)=CS2)C=C1O)O
Biological Activity: STK189682 is an ATPase inhibitor targeting MDA5, LGP2 and DDX1, with IC50 values of 7 μM, 7 μM and 5 μM, respectively. STK189682 binds to the MDA5-ATP complex in an ATP-noncompetitive manner and does not compete with RNA[1].
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STK189682 | STK189682 is an ATPase inhibitor targeting MDA5, LGP2 and DDX1, with IC50 values of 7 μM, 7 μM and 5 μM, respectively. STK189682 binds to the MDA5-ATP complex in an ATP-noncompetitive manner and does not compete with RNA. | |||||||||||||||||||||
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References
Keywords
