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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
DJ-1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "DJ-1" in MCE Product Catalog:
1
1 Cited Publications
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Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson's disease research [1].
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1 Cited Publications
Cat. No.: HY-P71625
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARK7; Parkinsonism-Associated Deglycase; Parkinsonism Associated Deglycase; Parkinson Disease Protein 7; DJ-1; Parkinson Protein 7; Protein/Nucleic Acid Deglycase DJ-1; Oncogene DJ1; Maillard Deglycase; Epididymis Secretory Sperm Binding Protein Li 67p;
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Neurotoxin Inhibitor is a neurotoxin inhibitor. Neurotoxin Inhibitor promotes the expression of DJ-1 protein, reduces the level of oxidative stress, and thereby protects dopaminergic neurons. Neurotoxin Inhibitor can be used for the study of Parkinson's disease [1].
Cat. No.: HY-162520
CAS No.: 797780-71-3
DJ-1-IN-1 (compound 797780-71-3) is a DJ-1 inhibitor. DJ-1-IN-1 exhibits antiproliferative activity in ACHN cells with an IC50 value of 12.18 μM and can inhibit the Wnt signaling pathway. DJ-1-IN-1 can be used in cancer research [1].
Cat. No.: HY-163562
CAS No.: 3117543-49-1
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JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research [1].
Cat. No.: HY-RS10043
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PARK7 Human Pre-designed siRNA Set A contains three designed siRNAs for PARK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153917
Purity: 99.64%
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CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theKdof 24 μM ofPGK1. CRT0063465 modulates the shelterin complex composition
and telomere Length [1].
Cat. No.: HY-P74653
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PARK7; Parkinsonism-Associated Deglycase; Parkinsonism Associated Deglycase; Parkinson Disease Protein 7; DJ-1; Parkinson Protein 7; Protein/Nucleic Acid Deglycase DJ-1; Oncogene DJ1; Maillard Deglycase; Epididymis Secretory Sperm Binding Protein Li 67p;
Cat. No.: HY-RS17611
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Park7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Park7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24071
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Park7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Park7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183448
CAS No.: 117666-86-1
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ETMTC is an orally active anti-inflammatory and antioxidant agent. ETMTC inhibits IKK-mediated phosphorylation and degradation of IkBα, blocks nuclear translocation and activation of NF-κB, and reduces the expression of ICAM-1, VCAM-1, E-selectin, Th2 cytokines and eosinophil chemokines. ETMTC abrogates neutrophil adhesion to endothelial monolayers and inhibits TNF-α-induced ROS production. ETMTC activates Nrf2, and enhances the activities of mitochondrial complex I and IV. ETMTC reduces lipid peroxidation levels, oxidative DNA damage, cytochrome c and caspase 9 activity, and decreases goblet cell metaplasia and subepithelial fibrosis. ETMTC can be used for the research of inflammatory diseases and asthma [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
