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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
DNA+aptamer
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "DNA+aptamer" in MCE Product Catalog:
Cat. No.: HY-160066
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SYL3C aptamer sodium is a DNA aptamer targeting EpCAM. SYL3C aptamer sodium targets a variety of cancer cell lines. SYL3C aptamer sodium can be used for targeted cancer cell imaging and circulating tumor cell detection .
Cat. No.: HY-177119
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ZBP1 Covalent PROTAC-1 is a covalent PROTAC degrader targeting ZBP1, with a DC50 of 25.69 nM. ZBP1 Covalent PROTAC-1 integrates a ZBP1-binding DNA aptamer, a linker containing covalent NASA, and an E3 ligase-recruiting moiety to guide ubiquitin-proteasome system-mediated degradation of ZBP1. ZBP1 Covalent PROTAC-1 exhibits inhibitory activity against necroptosis signaling pathways and inflammatory responses. ZBP1 Covalent PROTAC-1 can be used for research on viral pneumonia .
Cat. No.: HY-177655A
Synonyms: Fovista sodium
Pegpleranib (Fovista) sodium is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.
Cat. No.: HY-160050
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CD63-1 aptamer sodium is a high-affinity and specific DNA aptamer targeting the CD63 protein (Kd = 38.71 nM). CD63-1 aptamer sodium effectively binds to CD63-positive cells and serves as an exosome isolation reagent. CD63-1 aptamer sodium is applicable to breast cancer-related research .
Cat. No.: HY-177807
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DNMT1 aptamer sodium is a DNA aptamer for binding and inhibition of DNA methyltransferase 1 (DNMT1).
Cat. No.: HY-177655
CAS No.: 1618657-13-8
Synonyms: Fovista
Pegpleranib (Fovista) is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.
Cat. No.: HY-160045
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AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo .
Cat. No.: HY-177637
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H5N1 aptamer sodium is a DNA aptamer targeted to H5N1 Avian Influenza Virus.
Cat. No.: HY-177804
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Thrombin aptamer is a 11mer-DNA aptamer that targets thrombin. Thrombin aptamer inhibites thrombin-catalysed fibrin-clot formation in vitro
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DNA, 5'-CCTAACTGAGCTGTACTCGACTTATCCCGGATGGGGCTCTTAGG-3', sodium salt
Cat. No.: HY-177803
Cat. No.: HY-177823
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C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.
Cat. No.: HY-160063
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SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis .
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DNA, 5'-TAACCACCCCACCTCGCTCCCGTGACACTAATGCTAATTCCAA-3', sodium salt
Cat. No.: HY-160051
Cat. No.: HY-148826A
Synonyms: ARC 183 sodium; BC 007 sodium
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Rovunaptabin sodium (ARC 183 sodium) is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and specificity.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
