31 Results for "

Diazo

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "Diazo" in MCE Product Catalog:

14
6-Diazo-5-oxo-L-nor-Leucine
6-Diazo-5-oxo-L-nor-Leucine
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14 Publications Verification
Cat. No.: HY-108357
CAS No.: 157-03-9
Purity:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; DON
Target:  

Glutaminase Bacterial Influenza Virus Antibiotic

Research Areas:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
9
JHU-083
JHU-083
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9 Cited Publications
Cat. No.: HY-122218
CAS No.: 1998725-11-3
Purity:  ≥98.0%
Target:  

Glutaminase

Research Areas:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
1
Sudan Black B
Sudan Black B
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1 Cited Publications
Cat. No.: HY-D0213
CAS No.: 4197-25-5
Target:  

Environmental Pollutants Fluorescent Dye

Research Areas:  

Others

Sudan Black B, a fat-soluble diazo dye, is a histochemical stain. Sudan Black B can be used for staining of neutral triglycerides and lipids .
Fast Blue B Salt, Dye content ~95%
Fast Blue B Salt, Dye content ~95%
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Cat. No.: HY-W127711
CAS No.: 14263-94-6
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .
N6-Diazo-L-Fmoc-lysine
N6-Diazo-L-Fmoc-lysine
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Cat. No.: HY-W048205
CAS No.: 159610-89-6
Target:  

Amino Acid Derivatives

Research Areas:  

Others

N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Fl-DIBO
Fl-DIBO
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Cat. No.: HY-D1506
CAS No.: 1407523-31-2
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Sudan IV
Sudan IV
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Cat. No.: HY-D0932
CAS No.: 85-83-6
Synonyms: Solvent Red 24; C.I. 26105
Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .
Sudan I
Sudan I
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Cat. No.: HY-D0024
CAS No.: 842-07-9
Synonyms: Solvent Yellow 14
Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .
JHU395
JHU395
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Cat. No.: HY-128775
CAS No.: 2079938-92-2
Purity:  99.88%
Target:  

Drug Derivative

Research Areas:  

Cancer

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
Brilliant Yellow
Brilliant Yellow
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Cat. No.: HY-W110888
CAS No.: 3051-11-4
Brilliant Yellow, a diazo-containing sulfonic aci, is also a potent VGLUT-specific inhibitor. Brilliant Yellow is membrane-impermeable. However, there are some Brilliant Yellow analogs with low cytotoxicity and cell penetration. Brilliant Yellow analogs work on glutamatergic transmission in hippocampal neurons .
Diazo Biotin-PEG3-azide
Diazo Biotin-PEG3-azide
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Cat. No.: HY-140918
CAS No.: 1339202-33-3
Purity:  95.46%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Diazo Biotin-PEG3-alkyne
Diazo Biotin-PEG3-alkyne
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Cat. No.: HY-140925
CAS No.: 1884349-58-9
Purity:  98.07%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Fast garnet GBC sulfate salt, 90%
Fast garnet GBC sulfate salt, 90%
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Cat. No.: HY-W328317
CAS No.: 101-89-3
Synonyms: Azoic Diazo No. 4, 90%
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.
Sudan IV (Standard)
Sudan IV (Standard)
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Cat. No.: HY-D0932R
CAS No.: 85-83-6
Synonyms: Solvent Red 24 (Standard); C.I. 26105 (Standard)
Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.
Basic Brown 1
Basic Brown 1
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Cat. No.: HY-D0468
CAS No.: 10114-58-6
Basic Brown 1 is a diazo dyes .
6-Diazo-5-oxo-L-nor-Leucine (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard)
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Cat. No.: HY-108357R
CAS No.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); DON (Standard)
Target:  

Reference Standards Glutaminase Bacterial Influenza Virus Antibiotic

Research Areas:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
Direct Red 81
Direct Red 81
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Cat. No.: HY-D0334
CAS No.: 2610-11-9
Direct Red 81 is a diazo dye with a very high water solubility. The dye adsorption efficiency of Direct Red 81 is increased by increasing the adsorbent dose and adsorption time .
6-Diazo-5-oxo-D-norleucine
6-Diazo-5-oxo-D-norleucine
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Cat. No.: HY-W142025
CAS No.: 71629-86-2
Target:  

Amino Acid Derivatives γ-Glutamyl Transferase (GGT)

Research Areas:  

Metabolic Disease

6-Diazo-5-oxo-D-norleucine, a D-Glutamine (HY-100587) analog, is a γ-glutamyl transferase inhibitor .
Diazo Biotin-PEG3-DBCO
Diazo Biotin-PEG3-DBCO
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Cat. No.: HY-140930
Target:  

ADC Linkers

Research Areas:  

Cancer

Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Tetrazine-diazo-PEG4-biotin
Tetrazine-diazo-PEG4-biotin
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Cat. No.: HY-136078
Target:  

ADC Linkers

Research Areas:  

Cancer

Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Assay Types