85-83-6
85-83-6
Chemical Structure
Sudan IV
Synonym(s): Solvent Red 24; C.I. 26105
- CAS No.: 85-83-6
- Formula:C24H20N4O
- Molecular Weight:380.44
IUPAC Name: 1-((E)-(2-methyl-4-((E)-o-tolyldiazenyl)phenyl)diazenyl)naphthalen-2-ol
InChIKey: RCTGMCJBQGBLKT-PAMTUDGESA-N
SMILES: OC1=CC=C2C=CC=CC2=C1/N=N/C3=CC=C(/N=N/C4=CC=CC=C4C)C=C3C
Biological Activity: Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sudan IV | 98.0% | Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections. | ||||||||||||||||||||
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Sudan IV (Standard) | 97.24% | Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections. | ||||||||||||||||||||
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Sudan IV-d6 | 98.64% | Sudan IV-d6 (Solvent Red 24-d6) is the deuterium labeled Sudan IV(HY-D0932). Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections. | ||||||||||||||||||||
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Sudan I (Standard) | ≥98% | Sudan I (Standard) is the analytical standard of Sudan I. This product is intended for research and analytical applications. Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus. | ||||||||||||||||||||
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Solvent Red 1 (C.I.) (Standard) | ≥98% | Solvent Red 1 (C.I.) (Standard) is the analytical standard of Solvent Red 1 (C.I.). This product is intended for research and analytical applications. Solvent Red 1 (C.I.) is a red dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials. | ||||||||||||||||||||
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1-(2-Methoxyphenyl)azo-2-naphthol-d3 | 1-(2-Methoxyphenyl)azo-2-naphthol-d3 is the deuterium labeled 1-(2-Methoxyphenyl)azo-2-naphthol. | |||||||||||||||||||||
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C.I Acid orange 8 | C.I Acid orange 8 is an acidic orange dye that photochemically decolorizes during a UV/hydrogen peroxide process. | |||||||||||||||||||||
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Sudan II | Sudan Red II is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Sudan III (Standard) | ≥98% | Sudan III (Standard) is the analytical standard of Sudan III. This product is intended for research and analytical applications. Sudan III is a hydrophobic bisazo dye. | ||||||||||||||||||||
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Oil Red O | Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses. | |||||||||||||||||||||
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Janus red | Janus red is a basic dye. | |||||||||||||||||||||
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Solvent red 26 | Solvent red 26 is a biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Refat NA, et al. The induction of cytochrome P450 1A1 by sudan dyes. J Biochem Mol Toxicol. 2008 Mar-Apr;22(2):77-84. [Content Brief]
- [2]. Lu D, et al. Binding of Sudan II and Sudan IV to bovine serum albumin: comparison studies. Food Chem Toxicol. 2011 Dec;49(12):3158-64. [Content Brief]
- [3]. Huang ST, et al. An ultrasensitive and selective fluorescence assay for Sudan I and III against the influence of Sudan II and IV. Biosens Bioelectron. 2013 Apr 15;42:136-40. [Content Brief]
- [4]. Pérez-Sanz F, Riquelme-Pérez M, Martínez-Barba E, de la Peña-Moral J, Salazar Nicolás A, Carpes-Ruiz M, Esteban-Gil A, Legaz-García MDC, Parreño-González MA, Ramírez P, Martínez CM. Efficiency of Machine Learning Algorithms for the Determination of Macrovesicular Steatosis in Frozen Sections Stained with Sudan to Evaluate the Quality of the Graft in Liver Transplantation. Sensors (Basel). 2021 Mar 12;21(6):1993. [Content Brief]
