1 Result for "

DuP532

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DuP532" in MCE Product Catalog:

Cat. No.: HY-19094
CAS No.: 124750-95-4
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and heart failure. DuP-532 can react with a range of aryl and heteroaryl halides to form perfluoroalkyl(hetero)arenes in moderate to high yields. Computational studies of DuP-532 suggest that coordination of a second phenyl ring ligand may lower the energy barrier for decarboxylation of perfluorocarboxylates, thereby promoting the perfluoroalkylation reaction .
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