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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Dy
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Dy" in MCE Product Catalog:
3
3 Cited Publications
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DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM. DY268 can be used in the study of drug-induced liver injury (DILI) .
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Eosin Y (Acid Red 87 free base) is a soluble acid red dye molecule. Eosin Y has a wide application in organic synthesis as a photoredox catalyst. Eosin Y can be used as a component of Eosin-Nigrosin Sperm Viability Staining Solution (HY-DY2022) to assess sperm viability and identify the integrity of the membrane structure and function of inactive sperm .
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DY131 (GSK 9089) is a potent and selective ERRγ and ERRβ agonist. DY131displays inactive against ERRα, ERα and ERβ . DY131 also inhibits Smo signaling .
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Eosin Y disodium (Acid Red 87) is a soluble acid red dye molecule. Eosin Y disodium has a wide application in organic synthesis as a photoredox catalyst. Eosin Y disodium can be used as a component of Eosin-Nigrosin Sperm Viability Staining Solution (HY-DY2022) to assess sperm viability and identify the integrity of the membrane structure and function of inactive sperm .
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2 Cited Publications
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DY-46-2 is a high potency and selectivity novel non-nucleoside DNA methyltransferase 3A (DNMT3A) inhibitor with an IC50 value of 0.39 μM .
Cat. No.: HY-W013718
CAS No.: 869-52-3
Cat. No.: HY-W250145
CAS No.: 8005-03-6
Synonyms: Nigrosine
Cat. No.: HY-19230
CAS No.: 179185-73-0
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DY-9760e is a calmodulin (CaM) inhibitor. DY-9760e selectively inhibits the activity of various calmodulin-dependent enzymes by antagonizing the Ca²⁺/CaM complex, exhibiting the strongest inhibitory activity against nNOS, CaM kinase II, and calcineurin (Ki: 0.9, 1.4, and 2.0 μM, respectively). DY-9760e inhibits excessive nitric oxide production and protein tyrosine nitration, as well as the activation of calpain and caspase-3. DY-9760e reduces infarct size, improves cardiac function, and inhibits oxidative stress and cell death. DY-9760e can be used in research on the treatment of myocardial infarction, cerebral ischemia, and other diseases .
Cat. No.: HY-126298
CAS No.: 2340020-82-6
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAF V600E and B-RAF WT, respectively .
Cat. No.: HY-D2944
CAS No.: 1627942-39-5
Cat. No.: HY-D2949
CAS No.: 2836233-28-2
Cat. No.: HY-D2761
CAS No.: 1264737-80-5
Cat. No.: HY-D1495
CAS No.: 177194-52-4
Synonyms: Dy 880
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Fluorescent red NIR 880 is a fluorescent dye .
Cat. No.: HY-175080
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8-DY547-cGMP is a fluorescent cGMP analogue composed of a dye DY547 to position 8 of cGMP. 8-DY547-cGMP is a Cyclic nucleotide-gated A2 (CNGA2) ligand. 8-DY547-cGMP can activated CNGA2 channel. 8-DY547-cGMP can be used for simultaneously detection CNG channel activation and ligand binding .
Cat. No.: HY-110267R
CAS No.: 1609564-75-1
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DY268 (Standard) is the analytical standard of DY268 (HY-110267). This product is intended for research and analytical applications. DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM. DY268 can be used in the study of drug-induced liver injury (DILI) .
Cat. No.: HY-119396
CAS No.: 2020015-37-4
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DY3002 is a selective and highly potent EGFR inhibitor with activity in overcoming T790M-mediated drug resistance in non-small cell lung cancer. DY3002 exhibited superior inhibitory effects against EGFR T790M mutants in kinase assays (IC50 = 0.71 nM), compared to weaker inhibitory effects against wild-type EGFR (IC50 = 448.7 nM). DY3002 was significantly superior to rociletinib and osimertinib in selectivity, showing an extremely high selectivity index (SI = 632.0). In cell experiments, DY3002 had an IC50 value of 0.037 μM against H1975 cells, showing enhanced inhibitory potency. In addition, DY3002 was superior to other alternative compounds in terms of biological properties and did not cause hyperglycemia .
Cat. No.: HY-RS20977
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Lama2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lama2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
