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Results for "

EC 3.1.1.8

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (3) Cholinesterase (ChE) (1) Fungal (3) MicroRNA (4) Monocarboxylate Transporter (2) p62 (1) Reference Standards (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (2) Infection (6) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (1) miRNA antagomirs (1) miRNA agomirs (1) MicroRNAs (4) miRNA inhibitors (1)

Inhibitors & Agonists

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N4115

Syrosingopine 10+ Cited Publications Su 3118	Monocarboxylate Transporter	Cardiovascular Disease Cancer
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine .

HY-107126

Ibrexafungerp MK 3118; SCY-078	Fungal	Infection
Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .

HY-107126A

Ibrexafungerp citrate MK 3118 citrate; SCY-078 citrate	Fungal	Infection
Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .

HY-P2798

Cholinesterase, Horse serum EC 3.1.1.8; BCHE, Horse serum	Cholinesterase (ChE)	Neurological Disease
Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine .

HY-169779

PTX80	p62	Cancer
PTX80 is an antagonist of p62 with an IC₅₀ value of 31.18 nM. PTX80 reduces tumor volume in an HCT116 colorectal cancer mouse xenograft model .

HY-N4115R

Syrosingopine (Standard) Su 3118 (Standard)	Reference Standards Monocarboxylate Transporter	Cardiovascular Disease Cancer
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine .

HY-U00092B

(R,R)-BAY-Y 3118	Bacterial	Infection
(R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity .

HY-U00092

BAY-Y 3118	Bacterial	Infection
BAY-Y 3118 is a quinolone antibacterial agent. BAY-Y 3118 has a broad antibacterial spectrum in vitro. BAY-Y 3118 exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 can be used in the research of infectious diseases .

HY-R00549

*hsa-miR-3118* mimic**	MicroRNA	Cancer
hsa-miR-3118 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-3118 mimic hsa-miR-3118 mimic

HY-U00092A

*BAY-Y 3118* hydrochloride**	Bacterial	Infection
BAY-Y 3118 hydrochloride is a quinolone antibacterial agent. BAY-Y 3118 hydrochloride has a broad antibacterial spectrum in vitro. BAY-Y 3118 hydrochloride exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 hydrochloride shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 hydrochloride can be used in the research of infectious diseases .

HY-RI00549

*hsa-miR-3118* inhibitor**	MicroRNA	Cancer
hsa-miR-3118 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-3118 inhibitor hsa-miR-3118 inhibitor

HY-107126AR

Ibrexafungerp citrate (Standard) MK 3118 citrate (Standard); SCY-078 citrate (Standard)	Reference Standards Fungal	Infection
Ibrexafungerp citrate (Standard) (MK 3118 citrate (Standard)) is the analytical standard of Ibrexafungerp (citrate) (HY-107126A). This product is intended for research and analytical applications. Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .

HY-R00549A

*hsa-miR-3118* agomir**	MicroRNA	Cancer
hsa-miR-3118 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-3118 agomir hsa-miR-3118 agomir

HY-RI00549A

*hsa-miR-3118* antagomir**	MicroRNA	Cancer
hsa-miR-3118 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-3118 antagomir hsa-miR-3118 antagomir

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72859

	Butyrylcholinesterase/BCHE Protein, Mouse (HEK293, His) Cholinesterase; Acylcholine acylhydrolase; Choline esterase II; BCHE	Mouse	HEK293
	Butyrylcholinesterase (BCHE) Protein, an esterase with broad substrate specificity, crucially inactivates acetylcholine, maintaining neurotransmitter homeostasis. Beyond acetylcholine metabolism, BCHE degrades neurotoxic organophosphates, highlighting its detoxification role. The enzyme's versatility underscores its critical function in safeguarding against harmful effects of neurotoxic compounds. Butyrylcholinesterase/BCHE Protein, Mouse (HEK293, His) is the recombinant mouse-derived Butyrylcholinesterase/BCHE protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name		Classification

HY-R00549

*hsa-miR-3118* mimic**		MicroRNAs miRNA mimics
hsa-miR-3118 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00549

*hsa-miR-3118* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-3118 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00549A

*hsa-miR-3118* agomir**		MicroRNAs miRNA agomirs
hsa-miR-3118 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00549A

*hsa-miR-3118* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-3118 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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