51 Results for "

F11

" in MedChemExpress (MCE) Product Catalog:
Products (51)

51 Results for "F11" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P7041
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-33; IL-1F11; NF-HEV; DVS 27
Species:  
Source:  
2
2 Cited Publications
Cat. No.: HY-N0541
CAS No.: 69884-00-0
Synonyms: Ginsenoside A1
Pseudoginsenoside F11 is an orally active neuroprotective agent. Pseudoginsenoside F11 reduces the expression of β-amyloid precursor protein, inhibits the production of 1-40, downregulates the expression of JNK2, p53 and activated Caspase 3, and restores the activities of SOD and Glutathione peroxidase. Pseudoginsenoside F11 inhibits the excessive activation of μ-Calpain and restores the level of neuronal Nitric oxide synthase. Pseudoginsenoside F11 reduces infarct volume, alleviates cerebral edema, decreases neuronal loss, improves neurological deficits and enhances long-term functional outcomes in transient cerebral ischemia models. Pseudoginsenoside F11 antagonizes Methamphetamine-induced behavioral deficits, dopamine level reduction and neurotoxicity without altering the baseline behaviors of normal mice. Pseudoginsenoside F11 can be used in studies related to Alzheimer's disease, transient cerebral ischemic injury and Methamphetamine-induced neurotoxicity .
1
1 Cited Publications
Cat. No.: HY-162065
CAS No.: 851398-76-0
Target:  

Ferroptosis

Research Areas:  

Cancer

N6F11 is a selective ferroptosis inducer, and can selectively induce ferroptosis by targeting TRIM25-mediated GPX4 degradation in cancer cells while sparing immune cells. N6F11 initiates HMGB1-dependent antitumor immunity mediated by CD8 + T cells .
1
1 Cited Publications
Cat. No.: HY-P991124
CAS No.: 3008610-21-4
Synonyms: REGN-7508

Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

Cenvacibart is a monoclonal antibody with anticoagulant activity, targeting human coagulation factor XI (F11). Cenvacibart blocks the role of coagulation factor XI in the coagulation cascade, reducing thrombus formation. Cenvacibart is promising for research of thrombotic diseases .
1
1 Cited Publications
Cat. No.: HY-P70475
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
Source:  
1
1 Cited Publications
Cat. No.: HY-P70475AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
Source:  
1
1 Cited Publications
Cat. No.: HY-P73210
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; IL-1F11; NF-HEV; DVS 27
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Cat. No.: HY-P990743
CAS No.: 2704554-77-6
Synonyms: AB023; Xisomab 3G3; MAB 14E11

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Gruticibart is an anti-F11 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
Cat. No.: HY-N0541R
CAS No.: 69884-00-0
Synonyms: Ginsenoside A1 (Standard)
Pseudoginsenoside F11 (Standard) is the analytical standard of Pseudoginsenoside F11. This product is intended for research and analytical applications.
Cat. No.: HY-RS17241
Research Areas:  

Others

F11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for F11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-124084
CAS No.: 1673556-40-5
Research Areas:  

Cancer

SW203668 is an irreversible stearoyl CoA desaturase (SCD) inhibitor with an IC50 of 54 nM. SW203668 covalently binds and inhibits SCD, depletes unsaturated fatty acids, and triggers cell death in sensitive cells. SW203668 requires demethylation by CYP4F11 to form its active SCD-inhibiting form; differential CYP4F11 expression drives selective cytotoxicity. SW203668 exerts cytotoxicity toward CYP4F11-expressing non-small cell lung cancer (NSCLC) cells and spares CYP4F11-lacking NSCLC cells. SW203668 inhibits tumor growth in immunodeficient mice bearing CYP4F11-expressing NSCLC xenografts and spares mouse skin sebocytes. SW203668 can be used for the research of non-small cell lung cancer .
Cat. No.: HY-N6650
CAS No.: 20958-15-0
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
Cat. No.: HY-P10918
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

F11R peptide TFA is a F11 receptor molecule. F11R peptide TFA inhibits anti-F11R antibody-induced platelet aggregation, and inhibits the adhesion of platelets to cytokine (TNFα and INF-γ)-inflammed endothelial cells. F11R peptide TFA can be used for research of atherosclerotic plaques and associated thrombotic disease .
Cat. No.: HY-RS04625
Research Areas:  

Others

F11 Human Pre-designed siRNA Set A contains three designed siRNAs for F11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS23695
Research Areas:  

Others

F11 Rat Pre-designed siRNA Set A contains three designed siRNAs for F11 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-W472509
CAS No.: 73804-65-6
Synonyms: 11-Hydroxy-5,8,12,14-eicosatetraenoic acid
Target:  

Cytochrome P450

Research Areas:  

Cardiovascular Disease

11-HETE (11-Hydroxy-5,8,12,14-eicosatetraenoic acid) is the activator for cytochrome P450. 11-HETE upregulates the mRNA expressions of CYP1B1, CYP1A1, CYP4A11, CYP4F11, and CYP4F2, induces cell hypertrophy in RL-14 cell, and exhibits potential to be used in cardiovascular diseases .
Cat. No.: HY-W143313
CAS No.: 3710-31-4
Synonyms: 1,2-Dihydroxyheptane
1,2-Heptanediol is one of the components of some formulations (F11 and F12). 1,2-Heptanediol can be used in absorption studies of Metronidazole (HY-B0318) .
Cat. No.: HY-124084A
CAS No.: 2117405-48-6
Research Areas:  

Cancer

SW203668 TFA is an irreversible stearoyl CoA desaturase (SCD) inhibitor with an IC50 of 54 nM. SW203668 TFA covalently binds and inhibits SCD, depletes unsaturated fatty acids, and triggers cell death in sensitive cells. SW203668 TFA requires demethylation by CYP4F11 to form its active SCD-inhibiting form; differential CYP4F11 expression drives selective cytotoxicity. SW203668 TFA exerts cytotoxicity toward CYP4F11-expressing non-small cell lung cancer (NSCLC) cells and spares CYP4F11-lacking NSCLC cells. SW203668 TFA inhibits tumor growth in immunodeficient mice bearing CYP4F11-expressing NSCLC xenografts and spares mouse skin sebocytes. SW203668 TFA can be used for the research of non-small cell lung cancer .
Cat. No.: HY-P700978
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FXI; PTA; F11; Coagulation factor XI
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Cat. No.: HY-P703948
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Coagulation factor XI; FXI; PTA; F11
Species:  
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