Coagulation Factor XI/F11 Protein, Rabbit (HEK293, His)
Coagulation Factor XI/F11 Protein, Rabbit (HEK293, His) is the recombinant rabbit-derived Coagulation Factor XI/F11 protein, expressed by HEK293, with C-His tag.
- Species: Rabbit
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Coagulation Factor XI/F11 Protein, Rabbit (HEK293, His) is the recombinant rabbit-derived Coagulation Factor XI/F11 protein, expressed by HEK293, with C-His tag.
Background
Coagulation Factor XI, also known as F11, plays a pivotal role in the middle phase of the intrinsic pathway of blood coagulation. Its key function lies in activating Factor IX, contributing to the cascade of events that lead to the formation of a stable blood clot. Factor XI's role in the intrinsic pathway underscores its importance in the regulation of hemostasis, as it bridges the connection between upstream and downstream coagulation factors.
Technical Parameters
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Species Rabbit
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Source HEK293
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Tag C-8*His
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Accession
G1SSQ6 (E19-P624)
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Gene ID/
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Molecular Construction
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N-term
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Coagulation Factor XI/F11 (E19-P624)
Accession # G1SSQ6 -
8*His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
F11; Plasma Thromboplastin Antecedent; Coagulation Factor XI; Coagualtion Factor XI; FXI; PTA
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AA Sequence
ECVIKLFSDIYFQGGDITTVYTPNAKHCQVVCTYHPRCLLFTFMAESSVDSTKWFSCILKDSVTESLPKVNMTGAISGYSFKQCPHQLSACNKDIYVDLDMQGMNYNGSVTKNAQECQERCTNDAHCHFFTYATRQFPSAEHRNICLLKYTQTGAPTGIRKLKKVVSGFSLKSCALSNLACIRDIFPSTVFADNNIDSVVAPDALVCRRICTHHPNCLFFTFFSQEWPKESHRNLCLLKTSESGLPSTRIHKNQALSGFSLQNCRHSIPVFCHSSFYYDTDFLGEELDIVDVKGHEACQKMCTSAIRCQFFTYSSSQESHNKGKGTCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNVCTTKIKPRIVGGSASLPGEWPWQVTLHTVSPTQRHLCGGSIIGNQWILTAAHCFYGIESPKILRVYGGILNQSEIKEDTAFFGVQEIIIHDQYKTAESGYDIALLKLETTMNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLLSNEECRKRYQRHEITSGMICAGYKEGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGIYTNVVKYLDWILEKTQAP
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Predicted Molecular Mass
69.6 kDa
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Molecular Weight
Approximately 70-90 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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