3 Results for "

Furin Inhibitor II

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Furin Inhibitor II" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-P1028
CAS No.: 673202-67-0
Synonyms: Furin Inhibitor II
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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7
7 Cited Publications
Cat. No.: HY-P1028A
CAS No.: 958204-56-3
Synonyms: Furin Inhibitor II TFA
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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Cat. No.: HY-P10192
CAS No.: 717122-86-6
Synonyms: ABri peptide (1-23); ABri23
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Amyloid Bri Protein (1-23) (ABri peptide (1-23); ABri23) is a physiological 23-amino-acid peptide released from the C-terminus of the type II transmembrane protein Bri2 (ITM2B, Integral Membrane Protein 2B) following cleavage by the furin protease. Amyloid Bri Protein (1-23) interacts with the extracellular Brichos domain of Bri2 during Bri2 biosynthesis. Amyloid Bri Protein (1-23) interacts with amyloid β peptide (Aβ1-40, thereby inhibiting its aggregation and fibril formation. Amyloid Bri Protein (1-23) can be used in studies related to Alzheimer's disease and familial British dementia .
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