1 Result for "

GNE-9815

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GNE-9815" in MCE Product Catalog:

Cat. No.: HY-142160
CAS No.: 2729996-45-4
Purity:  98.94%
Target:  

Raf

Research Areas:  

Cancer

GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers .
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