20 Results for "

GPR54

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "GPR54" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P1022
CAS No.: 374683-24-6
Synonyms: Metastin(human)
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone .
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3
3 Cited Publications
Cat. No.: HY-P1197
CAS No.: 478507-53-8
Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
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3
3 Cited Publications
Cat. No.: HY-P1197A
Kisspeptin-10 (mouse, rat) TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 (mouse, rat) TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound .
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3
3 Cited Publications
Cat. No.: HY-P1022A
Synonyms: Metastin(human) TFA
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Kisspeptin-54(human) TFA (Metastin(human) TFA) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) TFA binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) TFA hinders tumor metastasis and stimulates gonadotropin secretion .
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2
2 Cited Publications
Cat. No.: HY-P0254
CAS No.: 374675-21-5
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease Cancer

Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression .
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2
2 Cited Publications
Cat. No.: HY-P0254A
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease Cancer

Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression .
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1
1 Cited Publications
Cat. No.: HY-P3641A
Target:  

GnRH Receptor

Kisspeptin 13 TFA is the TFA salt form of Kisspeptin 13 (HY-P3641). Kisspeptin-13 TFA inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 TFA activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. Kisspeptin 13 TFA interacts with α2-adrenergic and 5-HT2 serotonin receptors, exhibits antidepressant efficacy. Kisspeptin 13 TFA is an activator for GPR54 and GnRH receptor, which enhances memory and can be used in Alzheimer's disease research .
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Cat. No.: HY-P10489
CAS No.: 374675-19-1
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human is an endogenous ligand of KISS1R. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis .
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Cat. No.: HY-P1196A
CAS No.: 1848962-29-7
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease

Kisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10 .
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Cat. No.: HY-P11341
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology

Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .
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Cat. No.: HY-182421
CAS No.: 925924-27-2
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology Cancer

GPR54 antagonist‑1 is a GPR54 antagonist with IC50 values of 3.6 nM and 15 nM against human and rat GPR54, respectively. GPR54 antagonist‑1 shows blood‑brain barrier penetration. GPR54 antagonist‑1 blocks the function of human and rat GPR54 receptors. GPR54 antagonist‑1 suppresses plasma luteinizing hormone levels in castrated male rats. GPR54 antagonist‑1 can be used for the study of prostate cancer and endometriosis .
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Cat. No.: HY-P1196
CAS No.: 1145998-81-7
Target:  

Kisspeptin Receptor

Research Areas:  

Cardiovascular Disease

Kisspeptin 234, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 is an analog of Kisspeptin 10 .
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Cat. No.: HY-P10256A
Research Areas:  

Endocrinology

Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
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Cat. No.: HY-P3641
CAS No.: 374675-18-0
Target:  

GnRH Receptor

Kisspeptin 13 inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. Kisspeptin 13 interacts with α2-adrenergic and 5-HT2 serotonin receptors, exhibits antidepressant efficacy. Kisspeptin 13 is an activator for GPR54 and GnRH receptor, which enhances memory and can be used in Alzheimer's disease research .
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Cat. No.: HY-RS07316
Research Areas:  

Others

KISS1R Human Pre-designed siRNA Set A contains three designed siRNAs for KISS1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P10256
CAS No.: 1111070-93-9
Research Areas:  

Endocrinology

Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
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Cat. No.: HY-RS07318
Research Areas:  

Others

Kiss1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Kiss1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS07317
Research Areas:  

Others

Kiss1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kiss1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1414
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology

Canine KP-10 is a potent kisspeptin that elicits strong gonadotropin and estradiol responses in female dogs in estrus .
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Cat. No.: HY-P810743
Synonyms: AXOR12, GPR54, KISS1R, KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, hOT7T175

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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