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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
GSTA1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "GSTA1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P75153A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GSTA1; GTH1; Glutathione S-Transferase Alpha 1; Glutathione S-Transferase Ha Subunit 1; Glutathione S-Transferase A1; S-(Hydroxyalkyl)Glutathione Lyase A1; 13-Hydroperoxyoctadecadienoate Peroxidase; Glutathione S-Alkyltransferase A1; Androst-5-Ene-3,17-Di
Cat. No.: HY-RS05872
Target:
Research Areas:
GSTA1 Human Pre-designed siRNA Set A contains three designed siRNAs for GSTA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16237
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Gsta1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gsta1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25930
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Research Areas:
Gsta1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gsta1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W615446
CAS No.: 158890-32-5
Research Areas:
GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC50 of 0.11 μM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 (IC50 > 100 μM). GSTO1-IN-3 enhances the cytotoxicity of Cisplatin (HY-17394) against human breast cancer cells. GSTO1-IN-3 inhibits IL-1β release in mouse bone marrow-derived macrophage (BMDM) cells. GSTO1-IN-3 attenuates inflammation in mice. GSTO1-IN-3 can be used for breast cancer and inflammation research [1].
Cat. No.: HY-178372
CAS No.: 158890-33-6
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Research Areas:
GSTO1-IN-4 is a selective, potent GSTO1-1 inhibitor (IC50 = 0.04 μM; KI = 0.16 μM). GSTO1-IN-4 shows low inhibition to GSTO2-2, GSTA1-1 and GSTP1-1. GSTO1-IN-4 shows a capacity to attenuate inflammation in mice and to significantly enhance the cytotoxicity of Cisplatin (HY-17394). GSTO1-IN-4 can be used for the study of inflammation and breast cancer [1].
Cat. No.: HY-P75153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GSTA1; GTH1; Glutathione S-Transferase Alpha 1; Glutathione S-Transferase Ha Subunit 1; Glutathione S-Transferase A1; S-(Hydroxyalkyl)Glutathione Lyase A1; 13-Hydroperoxyoctadecadienoate Peroxidase; Glutathione S-Alkyltransferase A1; Androst-5-Ene-3,17-Di
Cat. No.: HY-N14116A
CAS No.: 8000-78-0
Target:
NF-κB NOD-like Receptor (NLR) Glutathione S-transferase Heme Oxygenase (HO) Quinone Reductase Bcl-2 Family Apoptosis Reactive Oxygen Species (ROS) Pyroptosis
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Garlic oil (synthetic) is an orally effective anti-inflammatory, antioxidant, and anticancer agent. Garlic oil (synthetic) inhibits the activation of NF-κB, NFκB2 and NLRP3 inflammasome, and induces the expression of GSTA1, HO-1 and NQO-1. Garlic oil (synthetic) reduces the Bcl-2/Bax protein ratio and activates NNK-induced apoptosis (apoptosis) in lung tissues. Garlic oil (synthetic) attenuates NNK-induced apoptosis in MRC-5 cells and reduces excessive ROS production. Garlic oil (synthetic) alleviates pyroptosis (pyroptosis) and exerts a protective effect against acute lung injury in mice. Garlic oil (synthetic) inhibits lung tumorigenesis in mice and improves small intestinal motility in rats with type 2 diabetes . Garlic oil (synthetic) can be used in research related to acute lung injury, lung cancer, peptic ulcer, type 2 diabetes and hypertension [1] .
Cat. No.: HY-182059
Research Areas:
GSTP1-IN-1 is a selective GSTP1 inhibitor with an IC50 of 0.79 μM and a Kd of 0.63 μM. GSTP1-IN-1 inhibits the proliferation of gastric cancer cells, induces ROS production and depletes glutathione. GSTP1-IN-1 achieves systemic exposure and is well tolerated in xenograft mouse models, while inhibiting tumor growth. GSTP1-IN-1 can be used in gastric cancer-related research [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
