GSTA1 Antibody
(Synonyms: Glutathione S-transferase alpha-1, 13-hydroperoxyoctadecadienoate peroxidase, GST 1-1, GST 1a-1a, GST A1-1, GST B, Glutathione S-transferase Ya-1, Ligandin, GST Ya1, Gsta1)GSTA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to GSTA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
GSTA1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to GSTA1.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 26 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 25 kDa
Purified recombinant protein of human GSTA1
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GSTA1 is a Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid[1][2][3].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Liver. -
Isoforms & Post-Translational Modification
GSTA1 has an amino acid length of 222, molecular weight is 25631 Da.
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Subunit
Homodimer or heterodimer of GSTA1 and GSTA2
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SwissProt ID
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Synonyms
Glutathione S-transferase alpha-1, 13-hydroperoxyoctadecadienoate peroxidase, GST 1-1, GST 1a-1a, GST A1-1, GST B, Glutathione S-transferase Ya-1, Ligandin, GST Ya1, Gsta1
Documentation
[1]. Bogaards JJ, et al. Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. Chem Res Toxicol. 1997 Mar;10(3):310-7. [Content Brief]
[2]. Pettersson PL, et al. The role of glutathione in the isomerization of delta 5-androstene-3,17-dione catalyzed by human glutathione transferase A1-1. J Biol Chem. 2001 Apr 13;276(15):11698-704. [Content Brief]
[3]. Seeley SK, et al. Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid. Biochim Biophys Acta. 2006 Jul;1760(7):1064-70. [Content Brief]
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