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Results for "

H1-0

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Peptides

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117889
    PARP14 inhibitor H10

    		PARP Apoptosis Cancer
    PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis .
    PARP14 inhibitor H10
  • HY-P5831
    Biotin-H10

    		Others MDM-2/p53 Cancer
    Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor with a KD of 6.4 nM. Biotin-H10 inhibits cancer cells viability .
    Biotin-H10
  • HY-RS05944
    H1-0 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    H1-0 Human Pre-designed siRNA Set A contains three designed siRNAs for H1-0 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    H1-0 Human Pre-designed siRNA Set A
    H1-0 Human Pre-designed siRNA Set A
  • HY-P11760
    HER2-targeted peptide H10

    		EGFR Cancer
    HER2-targeted peptide H10 is a HER2-targeting peptide with a Kd value of 30.4 nM. HER2-targeted peptide H10 specifically accumulates in HER2-positive tumor tissues of xenograft mice, when conjugated with nanoparticles. HER2-targeted peptide H10 can be used for studies related to HER2-positive breast cancer .
    HER2-targeted peptide H10
  • HY-162630
    HDAC6-IN-44

    		HDAC Inflammation/Immunology
    HDAC6-IN-44 (compound H10) is a selective HDAC6 inhibitor with an IC50 value of 8.97 nM. HDAC6-IN-44 can inhibit the idiopathic pulmonary fibrosis (IPF) phenotype and exhibits antifibrotic activity. Additionally, HDAC6-IN-44 reduces fibrogenesis in a bleomycin-induced pulmonary fibrosis mouse model and demonstrates good metabolic stability. HDAC6-IN-44 holds promise for research in the field of idiopathic pulmonary fibrosis .
    HDAC6-IN-44
  • HY-P11614
    LCA-H10

    		Liposome Cancer
    LCA-H10 is a lithocholic acid-histidine decapeptide conjugate, a biocompatible lipid nanoparticle (LNP) additive that reduces ionizable lipid proportions, functions as an endosomal escape inducer, and enhances siRNA encapsulation. LCA-H10 increases hepatic accumulation of LNPs in mice after intravenous injection when incorporated into LiLNP-LH and reduces proinflammatory cytokines (IL-6, TNF, IL-1β) in mouse serum. LCA-H10 can be used for the research of prostate cancer .
    LCA-H10

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