2084811-68-5

PARP14 inhibitor H10 Chemical Structure
2084811-68-5

Chemical Structure

PARP14 inhibitor H10

  • CAS No.: 2084811-68-5
  • Formula:C24H27N7O7S
  • Molecular Weight:557.58

IUPAC Name: 3-(N-(2-(4-(2-(4-((3-carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid

InChIKey: MUOMSHSMJCWQFH-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC(S(=O)(NCCN2N=NC(CCNC(CCC(NC3=CC=CC(C(N)=O)=C3)=O)=O)=C2)=O)=C1

Biological Activity: PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].

Cat. No. Product Name Purity Description Pricing
HY-117889 		PARP14 inhibitor H10 99.46% PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.
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