2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. CAM4066

CAM4066 is a potent CK2α inhibitor, with an IC50 value of 300 nM. CAM4066 exhibits high selectivity, with IC50 values of 22.35, 43.55, and > 50 μM for HIPK3, DAPK3, and CLK2, respectively. CAM4066 shows no cell activity. CAM4066 can be used for the development of highly potent CK2 inhibitors.

For research use only. We do not sell to patients.

CAM4066

CAM4066 Chemical Structure

CAS No. : 2101206-81-7

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CAM4066 Related Antibodies

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Description

CAM4066 is a potent CK2α inhibitor, with an IC50 value of 300 nM. CAM4066 exhibits high selectivity, with IC50 values of 22.35, 43.55, and > 50 μM for HIPK3, DAPK3, and CLK2, respectively. CAM4066 shows no cell activity. CAM4066 can be used for the development of highly potent CK2 inhibitors[1].
IC50 & Target[1]

CK2α

300 nM (IC50)

Molecular Weight

479.96

Formula

C26H26ClN3O4
CAS No.
SMILES

O=C(O)C1=CC=CC(NC(CCNC(CCNCC2=CC=C(C3=CC=CC=C3)C(Cl)=C2)=O)=O)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CAM4066 Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAM40662101206-81-7CAM 4066CAM-4066Casein KinaseCasein Kinase 2α (CK2α)Bivalent InhibitorCryptic aD PocketATP-competitiveKinase SelectivityStructure-Activity Relationship (SAR)X-ray CrystallographyInhibitorinhibitorinhibit

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