2101206-81-7
2101206-81-7
Chemical Structure
CAM4066
- CAS No.: 2101206-81-7
- Formula:C26H26ClN3O4
- Molecular Weight:479.96
IUPAC Name: 3-(3-(3-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)amino)propanamido)propanamido)benzoic acid
InChIKey: NZDQDPKZQDWCOF-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(NC(CCNC(CCNCC2=CC=C(C3=CC=CC=C3)C(Cl)=C2)=O)=O)=C1
Biological Activity:
CAM4066 is a potent CK2α inhibitor, with an IC50 value of 300 nM. CAM4066 exhibits high selectivity, with IC50 values of 22.35, 43.55, and > 50 μM for HIPK3, DAPK3, and CLK2, respectively. CAM4066 shows no cell activity. CAM4066 can be used for the development of highly potent CK2 inhibitors[1].
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CAM4066 | CAM4066 is a potent CK2α inhibitor, with an IC50 value of 300 nM. CAM4066 exhibits high selectivity, with IC50 values of 22.35, 43.55, and > 50 μM for HIPK3, DAPK3, and CLK2, respectively. CAM4066 shows no cell activity. CAM4066 can be used for the development of highly potent CK2 inhibitors. |
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