1. Cell Cycle/DNA Damage
    Epigenetics
    Apoptosis
  2. PARP
    Apoptosis
  3. PARP14 inhibitor H10

PARP14 inhibitor H10 

Cat. No.: HY-117889
Handling Instructions

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.

For research use only. We do not sell to patients.

PARP14 inhibitor H10 Chemical Structure

PARP14 inhibitor H10 Chemical Structure

CAS No. : 2084811-68-5

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Description

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].

IC50 & Target

PARP14

490 nM (IC50)

PARP1

 

Molecular Weight

557.58

Formula

C₂₄H₂₇N₇O₇S

CAS No.

2084811-68-5

SMILES

O=C(O)C1=CC=CC(S(=O)(NCCN2N=NC(CCNC(CCC(NC3=CC=CC(C(N)=O)=C3)=O)=O)=C2)=O)=C1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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PARP14 inhibitor H10
Cat. No.:
HY-117889
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