11 Results for "

H19

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "H19" in MCE Product Catalog:

Cat. No.: HY-137255
CAS No.: 64936-83-0
Synonyms: 3-Sulfotaurolithocholic acid disodium
Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6  and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
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Cat. No.: HY-113238A
CAS No.: 64936-81-8
Purity:  99.93%
Synonyms: Sulfolithocholic acid disodium; LCAS disodium
Lithocholic acid 3-sulfate disodium is a GPR39 agonist, with EC50 values of 41 μM and 42.4 μM in M39-20 and hGPR39-2 cells, respectively, in the absence of Zn 2+, and 0.88 μM and 0.97 μM in the presence of Zn 2+. Lithocholic acid 3-sulfate disodium acts as a RORγt ligand. Lithocholic acid 3-sulfate disodium stimulates the GPR39 receptor to initiate intracellular calcium signaling, independent of the Zn 2+-binding sites H17 and H19. LCA-3-S selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate disodium can be used in the research of cholestatic liver diseases .
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Cat. No.: HY-W587430
CAS No.: 64936-82-9
Synonyms: Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium
Target:  

HIV GPR39

Research Areas:  

Infection Inflammation/Immunology

Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9  and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
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Cat. No.: HY-173080
Target:  

Bacterial

Research Areas:  

Infection

Antibacterial agent 267 (Compound h19) is a pleuromutilin derivative with a potent antibacterial activity on Gram-positive bacteria. Antibacterial agent 267 shows an antibacterial activity in methicillin-resistant Staphylococcus aureus (MRSA)-infected mouse models .
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Cat. No.: HY-159119
Research Areas:  

Cancer

hDHODH-IN-15 (Compound H19) is an inhibitor for human dihydroguanylate dehydrogenase (hDHODH) with an IC50 of 0.21 µM. hDHODH-IN-15 exhibits cytotoxicity in cancer cells NCI-H226, HCT-116, and MDA-MB-231, with IC50 of 0.95-2.81 µM. hDHODH-IN-15 induces ferroptosis in HCT-116, and exhibits antitumor efficacy .
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Cat. No.: HY-P78738
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase, Type II; Peptidylarginine Deiminase II; Protein-Argini
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Cat. No.: HY-P78767
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase, Type II; Peptidylarginine Deiminase II; Protein-Argini
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Cat. No.: HY-P78767A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase, Type II; Peptidylarginine Deiminase II; Protein-Argini
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Cat. No.: HY-P78575
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase, Type II; Peptidylarginine Deiminase II; Protein-Argini
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Cat. No.: HY-P704802
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine Deiminase Type-2; Peptidyl Arginine Deiminase, Type II; Peptidylarginine Deiminase II; Protein-Argini
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Cat. No.: HY-P705883
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STK16; TSF1; Serine/Threonine Kinase 16; HPSK; PKL12; Protein Kinase Expressed In Day 12 Fetal Liver; MPSK; Non-Specific Serine/Threonine Protein Kinase; Myristoylated And Palmitoylated Serine/Threonine-Protein Kinase; TSF-1; Serine/Threonine-Protein Kina
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