hDHODH-IN-15

hDHODH-IN-15 (Compound H19) is an inhibitor for human dihydroguanylate dehydrogenase (hDHODH) with an IC50 of 0.21 µM. hDHODH-IN-15 exhibits cytotoxicity in cancer cells NCI-H226, HCT-116, and MDA-MB-231, with IC50 of 0.95-2.81 µM. hDHODH-IN-15 induces ferroptosis in HCT-116, and exhibits antitumor efficacy.

For research use only. We do not sell to patients.

  • Formula: C19H18N2O4
  • Molecular Weight:338.36
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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