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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
HAC
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "HAC" in MCE Product Catalog:
1
1 Cited Publications
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Acid Ceramidase-IN-1 is orally active and blood-brain barrier penetrant acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 reduces AC activity, accumulates ceramide species (Cer (d18:0/16:0), Cer (d18:1/16:0)), and decreases sphingosine levels. Acid Ceramidase-IN-1 can be used for the study of severe neurological lysosomal storage diseases (LSDs) such as Gaucher’s disease (GD) and Krabbe’s disease (KD) .
Cat. No.: HY-P6022
CAS No.: 774577-43-4
Cat. No.: HY-177136
CAS No.: 3009136-86-8
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ACLY-IN-2 (Compound 7) has inhibitory effect against human ATP citrate lyase (hACLY), with an IC50 of less than 1 nM. ACLY-IN-2 can be studied in research on liver-related diseases, type-2 diabetes, autoimmunity, and cancer .
Cat. No.: HY-P4827
CAS No.: 521986-14-1
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Cat. No.: HY-186084
CAS No.: 3098298-20-2
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ACSL5-IN-4 (the 9th compound in Table 115) is an ACS5 inhibitor, with its IC50 value for hACS5 being less than 100 nM. ACSL5-IN-4 can be used for research in digestive and oncological diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
