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Cat. No.: HY-117465

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HAC-Y6

HAC-Y6 has anticancer activity via cell cycle arrest. HAC-Y6 induces apoptosis in COLO 205 cells with an IC₅₀ of 0.52 µM.

For research use only. We do not sell to patients.

CAS No.: 1331959-78-4
Formula: C₂₃H₂₂N₂O₄
Molecular Weight:390.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

HAC-Y6 Chemical Structure

CAS No.: 1331959-78-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HAC-Y6 has anticancer activity via cell cycle arrest. HAC-Y6 induces apoptosis in COLO 205 cells with an IC₅₀ of 0.52 µM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
COLO 205	IC₅₀	0.52 μM Compound: 6	Cytotoxicity against human COLO205 cells Cytotoxicity against human COLO205 cells	[PMID: 26235951]
HL-60	IC₅₀	0.03 μM Compound: 6	Cytotoxicity against human HL60 cells Cytotoxicity against human HL60 cells	[PMID: 26235951]

Chemical Information

CAS No. 1331959-78-4
Molecular Weight 390.43
Formula C₂₃H₂₂N₂O₄
SMILES

O=C(C)C1=CC=C2C(C3=C(N2CC4=CC(OC)=C(C(OC)=C4)OC)N=CC=C3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yi-Chien Lin, et al. The novel synthetic compound 6-acetyl-9-(3,4,5-trimetho-xybenzyl)-9H-pyrido[2,3-b]indole induces mitotic arrest and apoptosis in human COLO 205 cells. Int J Oncol. 2013 Nov;43(5):1596-606. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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