5 Results for "

HB3

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "HB3" in MCE Product Catalog:

Cat. No.: HY-117015
CAS No.: 1038620-68-6
Purity:  99.44%
Target:  

Parasite

Research Areas:  

Infection

Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage .
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Cat. No.: HY-134914
CAS No.: 66508-53-0
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
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Cat. No.: HY-106515
CAS No.: 74129-03-6
Synonyms: WR228258
Target:  

Parasite

Research Areas:  

Infection

Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively .
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Cat. No.: HY-P10677
Target:  

Integrin

Research Areas:  

Cancer

HB-3-20 leads to degradation of the cell surface integrin αVβ5. Transglutaminase 2 (TG2) has specificity for HB-3-20 (kcat/KM=0.16 μM -1min -1) .
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Cat. No.: HY-RS07470
Research Areas:  

Others

KRT83 Human Pre-designed siRNA Set A contains three designed siRNAs for KRT83 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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