11 Results for "

HLX

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "HLX" in MCE Product Catalog:

Cat. No.: HY-177439
Research Areas:  

Cancer

HLX43 is an antibody-drug conjugate (ADC) targeting PD-L1. HLX43 consists of a human monoclonal antibody anti-PD-L1 antibody Opucolimab (HY-P99785) with the drug-linker conjugate being DL-01 (HY-155870A). HLX43 exerts superior anticancer efficacy with safety profile in vivo. HLX43 can be used for non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), esophageal squamous cell carcinoma (ESCC), melanoma (MEL), ovarian cancer (Ovc) research .
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Cat. No.: HY-P99118
CAS No.: 2231029-82-4
Synonyms: HLX 10

Target:  

PD-1/PD-L1 Akt STAT

Research Areas:  

Cancer

Serplulimab (HLX 10) is a humanized anti-PD-1 monoclonal antibody. Serplulimab can inhibit tumor growth, regulate the tumor microenvironment, and has anti-tumor activity. Serplulimab can be used in the research of cancer such as lung cancer and colon cancer .
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Cat. No.: HY-P991588
CAS No.: 2851060-90-5
Synonyms: AC101

Target:  

EGFR Apoptosis

Research Areas:  

Cancer

HLX-22 is a humanized monoclonal antibody targeting HER2. HLX-22 induces apoptosis in HER2-overexpressing breast and gastric cancer cells combined with Trastuzumab (HY-P9907). HLX-22 has potent antitumor activity against advanced solid tumors .
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Cat. No.: HY-P99785
CAS No.: 2251771-79-4
Synonyms: HLX20; HLX43 antibody

Research Areas:  

Cancer

Opucolimab (HLX20) is an engineered anti-PD-L1 humanised IgG1 antibody. Opucolimab, when conjugated with camptothecin toxoid, yields the PD-L1-targeting ADC, HLX43 (HY-177439). HLX43 can be used for non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), esophageal squamous cell carcinoma (ESCC), melanoma (MEL), ovarian cancer (Ovc) research .
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Cat. No.: HY-P99516
CAS No.: 2250342-36-8
Synonyms: HLX-06

Target:  

VEGFR

Research Areas:  

Cancer

Vulinacimab (HLX-06) is a human monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2). Vulinacimab specifically binds to and inhibits VEGFR-2, which may inhibit tumor angiogenesis and tumor cell proliferation. Vulinacimab can be used for the research of solid tumors and non-small cell lung cancer .
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Cat. No.: HY-P991605

Target:  

LAG-3

Research Areas:  

Cancer

HLX26 is a humanised anti-LAG-3 monoclonal antibody. HLX26 has antitumor activity especially advanced solid tumours. HLX26 can be used for lymphoma research .
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Cat. No.: HY-RS06221
Research Areas:  

Others

HLX Human Pre-designed siRNA Set A contains three designed siRNAs for HLX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-123773
CAS No.: 943344-76-1
Synonyms: NSC 732011; HLX-801
Research Areas:  

Cancer

SR-16157 (NSC 732011; HLX-801) is a dual-action steroid sulfatase (STS) inhibitor (IC50 = 0.1 uM) and selective ERα modulator. SR-16157 exhibits STS inhibitory and anti-estrogenic effects in breast cancer cells. SR-16157 may be used in breast cancer research .
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Cat. No.: HY-P992368

Target:  

TNF Receptor

Research Areas:  

Cancer

HLX51 is a regulatory T cell inhibitor and OX40/CD134/TNFRSF4 agonist with tumour growth inhibitory activity. HLX51 inhibits regulatory T cell differentiation and activity, relieves tumour microenvironment immunosuppression, enhances effector T cell function. HLX51 competitively binds OX40, activates OX40, promotes immune cell proliferation and T cell killing ability. HLX51 modulates immune cell function to inhibit tumour growth. HLX51 can be used for the research of advanced/metastatic solid tumours and lymphomas .
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Cat. No.: HY-P85434
Synonyms: HLX; HLX1; H2.0-like homeobox protein; Homeobox protein HB24; Homeobox protein HLX1

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat, Bovine, Dog, Pig

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Cat. No.: HY-P811182
Synonyms: HLX1, HLX, H2.0-like homeobox protein, Homeobox protein HB24, Homeobox protein HLX1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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