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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Human UGT1A9
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Human UGT1A9" in MCE Product Catalog:
Cat. No.: HY-E72111
Human UGT1A9 is a UDP-glucuronosyltransferase. UGT1A9 catalyzes the transfer of glucuronic acid from UDP-glucuronic acid (HY-N7033) to Umbelliferone (HY-N0573), 4-methylumbelliferone (HY-N0187), Scopoletin (HY-N0342), and α-Naphthol. Functional folding of UGT1A9 requires N-glycosylation; the deglycosylated mature protein still retains full activity .
6
6 Cited Publications
Cat. No.: HY-N0762
CAS No.: 31524-62-6
Cat. No.: HY-RS15433
Target:
Research Areas:
UGT1A9 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-135541
CAS No.: 365462-24-4
Synonyms: YM150 maleate
Target:
Research Areas:
Darexaban maleate (YM150 maleate) is a direct factor Xa inhibitor with activity in preventing venous thromboembolism. The major metabolite of Darexaban maleate in humans is Darexaban glucitol, which acts pharmacologically. The glucitolation reaction of Darexaban maleate is mainly catalyzed by UGT1A9 and UGT1A10 in the human liver and intestine. The K(m) value of Darexaban maleate glucitolation in the liver is greater than 250 μM, while in the intestine it exhibits substrate inhibition kinetics with a K(m) value of 27.3 μM. The unbound K(m) value of Darexaban maleate is significantly reduced by the influence of fatty acid-free bovine serum albumin in both HLM and UGT1A9 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
