14 Results for "

IL-36R

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "IL-36R" in MCE Product Catalog:

Cat. No.: HY-P99396
CAS No.: 2097104-58-8
Synonyms: BI 655130

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Spesolimab (BI 655130) is a mouse-derived humanized IgG1k antibody against IL-36R. IL-36 plays an important role in the immune system and Spesolimab is being investigated in palmoplantar pustulosis (PPP). Spesolimab was associated with a reduction in biomarkers associated with the innate, Th1/Th17 and neutrophil pathways .
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Cat. No.: HY-P99659
CAS No.: 2102543-86-0
Synonyms: ANB 019

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Imsidolimab (ANB 019) is a high-affinity, humanized monoclonal antibody of anti-IL-36R. Imsidolimab antagonizes IL-36 cytokine signal transduction. Imsidolimab has potential application in generalized pustular psoriasis (GPP) and other inflammatory skin diseases .
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Cat. No.: HY-RS06726
Research Areas:  

Others

IL1RL2 Human Pre-designed siRNA Set A contains three designed siRNAs for IL1RL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991281

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

REGN6490 is a humanized monoclonal anti-IL1RL2/IL-36R antibody. REGN6490 can be used in research related to pustular psoriasis .
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Cat. No.: HY-172660
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

36R-D481 is a competitive and orthosteric antagonist of IL-36R, effectively inhibiting IL-36 signaling. 36R-D481 can inhibit IL-36α and IL-36γ but not IL-36β induced IL-8 release .
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Cat. No.: HY-P992384

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

IMG-008 is a fully human antagonistic antibody targeting IL-36R, acting as a high-affinity IL-36R inhibitor (Kd = 6.23 pM). IMG-008 competitively blocks the pro-inflammatory signaling pathway mediated by human IL-36R, inhibiting receptor activation and the production of inflammatory cytokines. IMG-008 suppresses Imiquimod (HY-B0180)-induced skin inflammation in humanized mice, and Fc modification increases its serum exposure and prolongs its half-life. IMG-008 can be used in studies related to IL-36R-mediated inflammatory diseases such as psoriasis .
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Cat. No.: HY-P991468

Target:  

Interleukin Related

Research Areas:  

Cancer

IMM20324 is a human monoclonal antibody (mAb) targeting IL38. IMM20324 inhibits the interaction of IL-38 with human IL1RAPL1-Fc and human IL-36R-Fc with IC50 values of 1.267 nM and 1.4667 nM, respectively. IMM20324 has antitumor activity in the B16.F10 syngeneic mouse model. IMM20324 can be used in antitumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P78462
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
Species:  
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Cat. No.: HY-P70603
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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Cat. No.: HY-P70625
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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Cat. No.: HY-P78145
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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Cat. No.: HY-P70748
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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Cat. No.: HY-P77698
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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Cat. No.: HY-P78547
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL1RL2; Interleukin-1 Receptor-Related Protein 2; Interleukin 1 Receptor Like 2; Interleukin-1 Receptor-Like 2; IL1R-Rp2; IL-36 Receptor; IL1RRP2; IL-1Rrp2; IL-36R; IL-1 Receptor-Related Protein 2
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