1 Result for "

ITF 5924

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ITF 5924" in MCE Product Catalog:

Cat. No.: HY-161306
CAS No.: 2760854-72-4
Target:  

HDAC

Research Areas:  

Cancer

ITF5924 (compound 1) is a potent and highly selective HDAC6 inhibitor with an IC50 of 7.7 nM. ITF5924 shows greater than 104-fold selectivity for HDAC6 over all other HDAC subtypes. ITF5924 containing a difluoromethyl-1,3,4-oxadiazole (DFMO) moiety is slow-binding substrate analog of HDAC6 that undergo an enzyme-catalyzed ring opening reaction, forming a tight and long-lived enzyme-inhibitor complex .
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