1 Result for "

JNJ39729209

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNJ39729209" in MCE Product Catalog:

Cat. No.: HY-120476
CAS No.: 1160606-90-5
Target:  

TRP Channel

JNJ-39729209 is an antagonist for transient receptor potential vanilloid 1 (TRPV1) with pIC50 of 7.9, 8.5, 7.9 and 7.7 for TRPV1 from human, rat, canine and guinea pig. JNJ-39729209 inhibits Capsaicin (HY-10448)-induced hypotension and inhibit thereby hypothermia. JNJ-39729209 exhibits anti-inflammatory and analgesic activities in Carrageenan (HY-125474)- and CFA (HY-153808)-induced thermal hyperalgesia rat models. JNJ-39729209 exhibits anti-cough effects in guinea pigs .
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