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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
K-Ras G12C-IN-2
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "K-Ras G12C-IN-2" in MCE Product Catalog:
Cat. No.: HY-18605
CAS No.: 1629267-75-9
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.
PROTAC KRAS G12C (Compound 432) degrader-2 is a PROTAC degrader that targets KRAS G12C by recruiting cereblon. PROTAC KRAS G12C degrader-2 covalently modifies KRAS G12C. PROTAC KRAS G12C degrader-2 can be used for the research of non-small cell lung cancer .
Cat. No.: HY-U00416
CAS No.: 1698024-73-5
ARS-1323 is a KRAS G12C inhibitor. ARS-1323 specifically binds to the cysteine residue on the mutant K-Ras protein, locks it in the GDP-bound conformation, thereby blocking K-Ras activation and downstream signaling pathways. ARS-1323 can be used to investigate the signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C .
Cat. No.: HY-112492
CAS No.: 2206735-61-5
KRas G12C inhibitor 2 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1.
Cat. No.: HY-175583
CAS No.: 2725905-93-9
Research Areas:
KRASG12C ligand-2 is a KRas ligand used for PROTAC synthesis. KRASG12C ligand-2 serves as the target protein ligand of PROTAC KRAS G12C degrader-2 (HY-153821) .
Cat. No.: HY-W999529
CAS No.: 2725906-48-7
Research Areas:
KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
