1. GPCR/G Protein
  2. Ras
  3. K-Ras G12C-IN-2

K-Ras G12C-IN-2 

Cat. No.: HY-18605
Handling Instructions

K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.

For research use only. We do not sell to patients.

K-Ras G12C-IN-2 Chemical Structure

K-Ras G12C-IN-2 Chemical Structure

CAS No. : 1629267-75-9

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Description

K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.

IC50 & Target[1]

KRas G12C

 

In Vitro

K-Ras G12C-IN-2 is a covalent kras g12c inhibitor extracted from patent WO2014152588A1, compound V-35[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

418.92

Formula

C21H27ClN4O3

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 22 mg/mL (52.52 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3871 mL 11.9355 mL 23.8709 mL
5 mM 0.4774 mL 2.3871 mL 4.7742 mL
10 mM 0.2387 mL 1.1935 mL 2.3871 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.21%

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Product Name:
K-Ras G12C-IN-2
Cat. No.:
HY-18605
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