2725906-48-7

KRAS G12C degrader-2 Chemical Structure
2725906-48-7

Chemical Structure

KRAS G12C degrader-2

  • CAS No.: 2725906-48-7
  • Formula:C38H56N6O7S
  • Molecular Weight:740.96

IUPAC Name: tert-butyl 3-((1-(2-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethyl)piperidin-4-yl)oxy)azetidine-1-carboxylate

InChIKey: DLNRBBBQPXRTOU-PJCGKLBUSA-N

SMILES: C([C@@H](NC(CN1CCC(OC2CN(C(OC(C)(C)C)=O)C2)CC1)=O)[C@](C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C5=C(C)N=CS5)=O)C[C@@H](O)C3

Biological Activity: KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

Cat. No. Product Name Purity Description Pricing
HY-W999529
KRAS G12C degrader-2 KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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