KRAS G12C degrader-2
KRAS G12C degrader-2 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2725906-48-7
- Formula: C38H56N6O7S
- Molecular Weight:740.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2725906-48-7
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Molecular Weight 740.96
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Formula C38H56N6O7S
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SMILES
C([C@@H](NC(CN1CCC(OC2CN(C(OC(C)(C)C)=O)C2)CC1)=O)[C@](C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C5=C(C)N=CS5)=O)C[C@@H](O)C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRAS G12C degrader-2 Related Classifications
HY-W999529 Related Classifications
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