2378257-72-6
2378257-72-6
Chemical Structure
PROTAC KRAS G12C degrader-2
- No. CAS: 2378257-72-6
- Formula:C51H53ClFN9O7
- Molecular Weight:958.47
InChIKey: KZQITCSEFGTWRQ-OWAVIYFHSA-N
SMILES: FC1=C(C2=CC(O)=CC3=C2C=CC=C3)C(Cl)=CC4=C1N=C(O[C@H](C)CN5CCN(CC5)CC6CCN(C7=CC=C(C(N(C8C(NC(CC8)=O)=O)C9=O)=O)C9=C7)CC6)N=C4N%10CCN(CC%10)C(C=C)=O
Biological Activity: PROTAC KRAS G12C (Compound 432) degrader-2 is a PROTAC degrader that targets KRASG12C by recruiting cereblon. PROTAC KRAS G12C degrader-2 covalently modifies KRASG12C. PROTAC KRAS G12C degrader-2 can be used for the research of non-small cell lung cancer[1].
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PROTAC KRAS G12C degrader-2 | 98.45% | PROTAC KRAS G12C (Compound 432) degrader-2 is a PROTAC degrader that targets KRASG12C by recruiting cereblon. PROTAC KRAS G12C degrader-2 covalently modifies KRASG12C. PROTAC KRAS G12C degrader-2 can be used for the research of non-small cell lung cancer. | ||||||||||||||||||||
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References
Keywords
