2 Results for "

KIN8194

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KIN8194" in MCE Product Catalog:

Cat. No.: HY-15805
CAS No.: 330786-01-1
Purity:  98.01%
Target:  

Src Btk

Research Areas:  

Cancer

KIN-8194 is an orally active dual inhibitor of HCK and BTK, with IC50 values of 0.915 and <0.495 nM, respectively. KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma (MCL). KIN-8194 overcomes ibrutinib (HY-10997) resistance with a survival benefit in TMD-8 ABC DLBCL xenografted mice .
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Cat. No.: HY-15805A
CAS No.: 330792-60-4
Target:  

Drug Isomer

Research Areas:  

Others

cis-KIN-8194 is the cis-isomer of KIN-8194 (HY-15805)
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